6TTP: Crystal structure of the human METTL3-METTL14 complex bound to Compound 1/Adenosine (DHU_M3M_023)

PDB ID: 6TTPDownload
MMDB ID: 184931
PDB Deposition Date: 2019/12/30
Updated in MMDB: 2020/09
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6TTP: dimeric; determined by author and by software (PISA)
Molecular Components in 6TTP
Label Count Molecule
Proteins (2 molecules)
1
N6-adenosine-methyltransferase Catalytic Subunit
(Gene symbol: METTL3)
Molecule annotation
1
N6-adenosine-methyltransferase Non-catalytic Subunit
(Gene symbol: METTL14)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ADENOSINEADENOSINE
2
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303