6XJP: Crystal Structure of KPT-185 bound to CRM1 (537-DLTVK-541 to GLCEQ)

PDB ID: 6XJPDownload
MMDB ID: 197947
PDB Deposition Date: 2020/6/24
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.802  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 6XJP: trimeric; determined by author
Molecular Components in 6XJP
Label Count Molecule
Proteins (3 molecules)
1
Gtp-binding Nuclear Protein RAN
Molecule annotation
1
Ran-specific Gtpase-activating Protein 1
Molecule annotation
1
Exportin-1
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
propan-2-yl 3-{3-[3-methoxy-5-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}propanoatepropan-2-yl 3-{3-[3-methoxy-5-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}propanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303