National Center for
Biotechnology Information

6ZP4: SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2

PDB ID:

6ZP4 Download

MMDB ID:

191073

PDB Deposition Date:

2020/7/8

Updated in MMDB:

2022/11

Experimental Method:

electron microscopy

Resolution:

2.9 Å

Source Organism:

Severe acute respiratory syndrome coronavirus 2▼

Taxonomy	Molecule
Severe acute respiratory syndrome coronavirus 2	J
Homo sapiens	a, p, d, Q, q, W, r, s, t, c, n, m, y, D, z, R, T, 2, w, b, e, u, v, o, g, k, x, h, P, S, l, U, V, i , j, G, I, B, A, C, E, F, H, K, L, M, N, X, 1, 4, O, Y, Z

Similar Structures:

Biological Unit for 6ZP4: 54-meric; determined by author

Molecular Components in 6ZP4
Label	Count	Molecule
Proteins (52 molecules)
a	1	40S Ribosomal Protein SA
p	1	40S Ribosomal Protein S3A
d	1	40S Ribosomal Protein S2
Q	1	40S Ribosomal Protein S26
q	1	40S Ribosomal Protein S4, X Isoform
W	1	60S Ribosomal Protein L41
r	1	40S Ribosomal Protein S6
s	1	40S Ribosomal Protein S7
t	1	40S Ribosomal Protein S8
c	1	40S Ribosomal Protein S9
n	1	40S Ribosomal Protein S11
m	1	40S Ribosomal Protein S13
y	1	40S Ribosomal Protein S21
D	1	40S Ribosomal Protein S15a
z	1	40S Ribosomal Protein S24
R	1	40S Ribosomal Protein S27
T	1	40S Ribosomal Protein S30
w	1	40S Ribosomal Protein S17
b	1	40S Ribosomal Protein S3
e	1	40S Ribosomal Protein S5
u	1	40S Ribosomal Protein S10
v	1	40S Ribosomal Protein S12
o	1	40S Ribosomal Protein S15
g	1	40S Ribosomal Protein S16
k	1	40S Ribosomal Protein S18
x	1	40S Ribosomal Protein S19
h	1	40S Ribosomal Protein S20
P	1	40S Ribosomal Protein S25
S	1	40S Ribosomal Protein S28
l	1	40S Ribosomal Protein S29
U	1	Ubiquitin-40s Ribosomal Protein S27a
V	1	Receptor of Activated Protein C Kinase 1
i	1	40S Ribosomal Protein S14
j	1	40S Ribosomal Protein S23
G	1	Eukaryotic Translation Initiation Factor 1A, X-chromosomal
I	1	Eukaryotic Translation Initiation Factor 3 Subunit I
B	1	Eukaryotic Translation Initiation Factor 3 Subunit B
A	1	Eukaryotic Translation Initiation Factor 3 Subunit a
C	1	Eukaryotic Translation Initiation Factor 3 Subunit C
E	1	Eukaryotic Translation Initiation Factor 3 Subunit E
F	1	Eukaryotic Translation Initiation Factor 3 Subunit F
H	1	Eukaryotic Translation Initiation Factor 3 Subunit H
K	1	Eukaryotic Translation Initiation Factor 3 Subunit K
L	1	Eukaryotic Translation Initiation Factor 3 Subunit L
M	1	Eukaryotic Translation Initiation Factor 3 Subunit M
N	1	Eukaryotic Translation Initiation Factor 3 Subunit D
X	1	Unknown Factor
4	1	Eukaryotic Translation Initiation Factor 2 Subunit 2
O	1	Eukaryotic Translation Initiation Factor 2 Subunit 1
Y	1	Eukaryotic Translation Initiation Factor 2 Subunit 3
Z	1	Eukaryotic Translation Initiation Factor 1
J	1	Non-structural Protein 1
Nucleotides(2 molecules)
2	1	18S Ribosomal RNA
1	1	tRNA
Chemicals and Non-standard biopolymers (6 molecules)
1	4	ZINC ION
2	1	GUANOSINE-5'-TRIPHOSPHATE
3	1	MAGNESIUM ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303