National Center for
Biotechnology Information

7SYV: Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)

PDB ID:

MMDB ID:

218067

PDB Deposition Date:

2021/11/25

Updated in MMDB:

2024/10

Experimental Method:

electron microscopy

Resolution:

3.9 Å

Source Organism:

hepatitis C virus genotype 1a▼

Taxonomy	Molecule
hepatitis C virus genotype 1a	z
Oryctolagus cuniculus	2, Z, a, B, b, C, c, D, d, E, e, F, f, G, g, H, h, I, i, J, n, K, x, L, M, N, O, P, Q, R, S, T, U, V , W, X, Y
Homo sapiens	A

Similar Structures:

Biological Unit for 7SYV: 39-meric; determined by author

Molecular Components in 7SYV
Label	Count	Molecule
Proteins (36 molecules)
Z	1	40S Ribosomal Protein S24
A	1	Eukaryotic Translation Initiation Factor 1A, X-chromosomal
a	1	40S Ribosomal Protein S25
B	1	40S Ribosomal Protein SA
b	1	Es26
C	1	ES1
c	1	Es27
D	1	40S Ribosomal Protein S2
d	1	Es28
E	1	US3
e	1	Es29
F	1	40S Ribosomal Protein S4
f	1	Es30
G	1	US7
g	1	40S Ribosomal Protein S27a
H	1	ES6
h	1	Rack1
I	1	40S Ribosomal Protein S7
J	1	ES8
n	1	60S Ribosomal Protein L41
K	1	US4
x	1	Eukaryotic Translation Initiation Factor 5B
L	1	Es10
M	1	Us17
N	1	Es12
O	1	Us15
P	1	Us11
Q	1	Us19
R	1	US9
S	1	Es17
T	1	Us13
U	1	Es19
V	1	Us10
W	1	40S Ribosomal Protein S21
X	1	US8
Y	1	Us12
Nucleotides(3 molecules)
2	1	18S rRNA
i	1	Met-trna-i-met
z	1	HCV Ires
Chemicals and Non-standard biopolymers (5 molecules)
1	2	ZINC ION
2	1	GUANOSINE-5'-TRIPHOSPHATE
3	1	MAGNESIUM ION
4	1	SODIUM ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB