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8AKC:
Human Sirt6 in complex with ADP-ribose and fragment 3-(acetylamino)thiophene-2-carboxylic acid
PDB ID:
8AKC
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MMDB ID:
234140
PDB Deposition Date:
2022/7/29
Updated in MMDB:
2023/08
Experimental Method:
x-ray diffraction
Resolution:
1.83 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8AKC: monomeric; determined by author
Molecular Components in 8AKC
Label
Count
Molecule
Protein (1 molecule)
A
1
Nad-dependent Protein Deacetylase Sirtuin-6
(Gene symbol:
SIRT6
)
Chemicals and Non-standard biopolymers (12 molecules)
1
2
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
2
1
ZINC ION
3
3
DI(HYDROXYETHYL)ETHER
4
4
SULFATE ION
5
1
3-(acetylamino)thiophene-2-carboxylic acid
6
1
CHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303