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8BW9:
Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP
PDB ID:
8BW9
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MMDB ID:
242879
PDB Deposition Date:
2022/12/6
Updated in MMDB:
2024/08
Experimental Method:
electron microscopy
Resolution:
3.32 Å
Source Organism:
Drosophila melanogaster
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8BW9: tetrameric; determined by author and by software (PISA)
Molecular Components in 8BW9
Label
Count
Molecule
Proteins (4 molecules)
A
1
Protein Aveugle
(Gene symbol:
ave
)
B
1
Connector Enhancer of KSR Protein CNK
(Gene symbol:
cnk
)
C
1
Dual Specificity Mitogen-activated Protein Kinase Kinase Dsor1
(Gene symbol:
Dsor1
)
D
1
KSR
(Gene symbol:
ksr
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
2
1
Trametinib
3
1
MAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303