Locust plagues are one of the main biological disasters occurring in grassland, posing a
serious threat to agriculture, animal husbandry, and grassland ecological security. More...
Locust plagues are one of the main biological disasters occurring in grassland, posing a
serious threat to agriculture, animal husbandry, and grassland ecological security. Matrine is a highly
potent plant pesticide that, when applied artificially, may efficiently manage the number of locusts
in their natural habitat. In order to determine the specific genes and proteins that are affected by
matrine and play a role in regulating metabolism in the locust species Oedaleus asiaticus, we
conducted RNA-seq, proteomic sequencing, and bioinformatics analyses on third-instar nymphs.
These nymphs were divided into two groups: one group was grown under normal conditions, while
the other group was treated with matrine. The purpose of this investigation was to gain insight into
the molecular mechanisms underlying matrine resistance. Genes and proteins that exhibited
differential expression were identified and subjected to analysis using bioinformatics software.
Additionally, enrichment studies based on Gene Ontology (GO) and the Kyoto Encyclopedia of
Genes and Genomes (KEGG) were performed. The findings demonstrated that matrine exerted
control of the growth of O. asiaticus via modulating the synthesis of chitin and hormones. Increased
expression of detoxifying enzymes was observed, which may be related to matrine detoxification.
These findings provide a basis for better comprehension of the molecular mechanism behind the
regulation of development mediated by matrine in Asian locust hoppers. Less...