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Genome Information for Trypanosoma brucei
We used an in vitro system to obtain Trypanosoma brucei metacyclics and determined their mRNA repertoires by mRNA sequencing in comparison to non-infectious procyclic trypanosomes.
More...We used an in vitro system to obtain Trypanosoma brucei metacyclics and determined their mRNA repertoires by mRNA sequencing in comparison to non-infectious procyclic trypanosomes. We show that metacyclics are quiescent cells, and we propose that the transition to this quiescent state is a factor in the choice of a “minimalistic” metacyclic variant surface glycoprotein (VSG) expression site, because it requires fewer cellular resources for activation
Less...Accession | PRJNA381815 |
Data Type | Transcriptome or Gene expression |
Scope | Monoisolate |
Organism | Trypanosoma brucei brucei TREU927[Taxonomy ID: 185431] Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma; Trypanosoma brucei; Trypanosoma brucei brucei TREU927 |
Grants | - "RNA METABOLISM IN TRYPANOSOMES: RNA Metabolism in Trypanosomes" (Grant ID R01 AI028798, National Institute of Allergy and Infectious Diseases Extramural Activities)
- "Mechanism of Infectivity Acquisition in African Trypanosomes" (Grant ID R01 AI110325, National Institute of Allergy and Infectious Diseases Extramural Activities)
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Submission | Registration date: 5-Apr-2017 Yale School of Public Health |
Project Data:
Resource Name | Number of Links |
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BioSample | 1 |
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