GEO DataSets for BioProject (Select 138655) - GEO DataSets

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Items: 2

Select item 2000293161.

Expression data from colon fibroblasts treated with Sonic hedgehog homolog (SHH)

(Submitter supplied) Canonical Hedgehog (Hh) signaling regulates the expression of genes that are critical to the patterning and development of a variety of organ systems. In adult, both ligand-dependent and ligand-independent Hh pathway activation are known to promote tumorigenesis. Recent studies have shown that in tumors promoted by Hh ligand, activation occurs within the stromal microenvironment (Yauch et al., 2009). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4512
Platform:: GPL570
6 Samples

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Accession:: GSE29316

ID:: 200029316

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45122.

Sonic hedgehog homolog-stimulated fibroblasts

Analysis of CCD-18Co colon myofibroblasts stimulated with Sonic hedgehog homolog (SHH) for 72hr. Hedgehog (Hh)-driven, CCD-18Co proangiogenic signals drive tumor angiogenesis in vitro and in vivo. Results provide insight into the molecular mechanisms underlying Hh regulation of tumor angiogenesis.