BioProject

The fundamental biological functions of a living cell are stored within the DNA sequence of its genome. More...

The fundamental biological functions of a living cell are stored within the DNA sequence of its genome. It is argued that the rewriting of entire genomes through the process of chemical synthesis provides a powerful and complementary research concept to understand how essential functions are programmed into genomes. This project focuses on the chemical-synthesis rewriting and functional assessment of an 785kb artificial bacterial genome termed Caulobacter ethensis 2.0, which comprises all essential genes of the cell-cycle model organism Caulobacter crescentus necessary for growth under rich media conditions. Less...