U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GM22129 male affected TAZ sample

Identifiers
BioSample: SAMN00806158; Coriell: GM22129
Organism
Homo sapiens (human)
cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo
Attributes
cell lineGM22129
sexMale
cell typeB-Lymphocyte
raceCaucasian
ethnicityITALIAN/IRISH/ENGLISH
age11 YR
GeneTAZ
affected_byTAZ
MutationIVS1+5G>A
collectionNIGMS Human Genetic Cell Repository
Tags
TAZ
BTHS
Barth syndrome
Tafazzin
Description

Clinically affected;no family history;onset of dilated cardiomyopathy at birth;neutropenia;growth retardation;skeletal muscle weakness;several infections;cholesterol at >1 year of age was 95 mg/dl (LDL 41);normal carnitine;3-methylglutaconate in plasma is 2594 nmol/l and in urine is 106;muscle biopsy showed abnormal mitochondria;donor subject is hemizygous for a donor splice site mutation in the TAZ (G4.5) gene: IVS1+5G>A

Submission
Coriell; 2012-03-05
Accession:
SAMN00806158
ID:
806158

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center