Table 6.

Recommended Surveillance for Individuals with Thiamine-Responsive Megaloblastic Anemia Syndrome

System/ConcernEvaluationFrequency
Hematologic Hematologic tests (CBC, reticulocyte count)At least annually
Hearing Hearing test
Endocrine
  • Assess for glucose intolerance (fasting serum glucose concentration, OGTT, urinalysis).
  • Assess for clinical manifestations of poor glycemic control.
Eyes Ophthalmologic eval
Cardiac Cardiac eval; EKG
Neurologic Neurologic eval

CBC = complete blood count; OGTT = oral glucose tolerance test

From: Thiamine-Responsive Megaloblastic Anemia Syndrome

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