Overview

The magnitude of the dengue problem has increased dramatically and has extended geographically to many previously unaffected areas. It remains the most important arthropod-borne viral disease of humans.

This new edition has been produced to make widely available to health practitioners,laboratory personnel, those involved in vector control and other public health officials, a concise source of information of worldwide relevance on dengue.

The guidelines provide updated practical information on the clinical management and delivery of clinical services; vector management and delivery of vector control services; laboratory diagnosis and diagnostic tests; and surveillance, emergency preparedness and response.

Contents

• PREFACE
• METHODOLOGY
• ACKNOWLEDGEMENTS
• ABBREVIATIONS
• 1. EPIDEMIOLOGY, BURDEN OF DISEASE AND TRANSMISSION
  • 1.1 DENGUE EPIDEMIOLOGY
  • 1.2 BURDEN OF DISEASE
  • 1.3 DENGUE IN INTERNATIONAL TRAVEL
  • 1.4 TRANSMISSION
  • 1.5 REFERENCES
• 2. CLINICAL MANAGEMENT AND DELIVERY OF CLINICAL SERVICES
  • 2.1 OVERVIEW
  • 2.2 DELIVERY OF CLINICAL SERVICES AND CASE MANAGEMENT
  • 2.3 RECOMMENDATIONS FOR TREATMENT
  • 2.4 REFERENCES
• 3. VECTOR MANAGEMENT AND DELIVERY OF VECTOR CONTROL SERVICES
  • 3.1 OVERVIEW
  • 3.2 METHODS OF VECTOR CONTROL
  • 3.3 DELIVERY OF VECTOR CONTROL INTERVENTIONS
  • 3.4 REFERENCES
• 4. LABORATORY DIAGNOSIS AND DIAGNOSTIC TESTS
  • 4.1 OVERVIEW
  • 4.2 CONSIDERATIONS IN THE CHOICE OF DIAGNOSTIC METHODS
  • 4.3 CURRENT DENGUE DIAGNOSTIC METHODS
  • 4.4 FUTURE TEST DEVELOPMENTS
  • 4.5 QUALITY ASSURANCE
  • 4.6 BIOSAFETY ISSUES
  • 4.7 ORGANIZATION OF LABORATORY SERVICES
  • 4.8 REFERENCES
• 5. SURVEILLANCE, EMERGENCY PREPAREDNESS AND RESPONSE
  • 5.1 OVERVIEW
  • 5.2 DENGUE SURVEILLANCE
  • 5.3 DENGUE PREPAREDNESS PLANNING AND RESPONSE
  • 5.4 PROGRAMME ASSESSMENT
  • 5.5 REFERENCES
• 6. NEW AVENUES
  • 6.1 OVERVIEW
  • 6.2 DENGUE VACCINES
  • 6.3 DENGUE ANTIVIRAL DRUGS
  • 6.4 REFERENCES

A joint publication of the World Health Organization (WHO) and the Special Programme for Research and Training in Tropical Diseases (TDR)

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