Figure 13. Immunofluorescent staining for the HSV DNA replication protein UL29.

Figure 13Immunofluorescent staining for the HSV DNA replication protein UL29

MRC-5 cells were infected with HSV-1 (0.1 MOI) for 8 hr, followed by the addition of DMSO, ACV (100 μM), or ML324 (50 μM) for 12 hr. Cells were stained with anti-UL29 (green), Dapi (blue), and Phalloidin-647 (F-actin, red).

From: Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity

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