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Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024.

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Figure 5. . Gluten-reactive CD4+ T-helper cells (with cell-surface CD4 markers) become activated upon recognition by a T-cell receptor of gluten peptides presented by HLA-DQ2 or HLA-DQ8 protein molecules on the surface of antigen-presenting cells (APCs) in the lamina propria.

Figure 5.

Gluten-reactive CD4+ T-helper cells (with cell-surface CD4 markers) become activated upon recognition by a T-cell receptor of gluten peptides presented by HLA-DQ2 or HLA-DQ8 protein molecules on the surface of antigen-presenting cells (APCs) in the lamina propria.

Modified and expanded from Sollid [2002]. With permission from LM Sollid, MD.

From: Celiac Disease

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