Figure F-12 is a plot demonstrating consistency within the following closed treatment loops: high estrogen/standard estrogen/ultrlow-low estrogen; high estrogen/standard estrogen/placebo; high estrogen/ultralow-low estrogen/placebo; standard estrogen/ultralow-low estrogen/black cohosh; standard estrogen/ultralow-low estrogen/placebo; standard estrogen/black cohosh/placebo; ultralow-low estrogen/black cohosh/placebo; ultralow-low estrogen/isoflavones/placebo. The plot shows that the only inconsistency among the treatment loops was found in the loop of standard estrogen/ultralow-low estrogen/black cohosh.

Figure F-12Plot showing consistency of closed loops with letters representing treatmentsa

a: high dose estrogen; b: standard dose estrogen; c: low/ultralow dose estrogen; d: SSRI/SNRI; f: isoflavones; g: black cohosh; I: placebo.

a

Inconsistency (95% CI excluding 0) is evident only in the treatment loop including standard dose estrogen-low/ultralow dose estrogen-black cohosh.

From: Appendix F, Vasomotor Symptom Supplemental Tables and Plots

Cover of Menopausal Symptoms: Comparative Effectiveness of Therapies
Menopausal Symptoms: Comparative Effectiveness of Therapies [Internet].
Comparative Effectiveness Reviews, No. 147.
Grant MD, Marbella A, Wang AT, et al.
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