Figure 24 is titled “Standardized mean change from baseline in anxiety symptoms (HAM-A) for selective serotonin reuptake inhibitors compared with placebo.” The figure displays a forest plot reporting the standardized mean difference in HAM-A stratified by fluoxetine compared with placebo and sertraline compared with placebo. This figure is described further in the “Prevention or Reduction of Comorbid Medical or Psychiatric Conditions” section as follows: “Four trials assessed the efficacy of SSRIs for anxiety symptoms. Both fluoxetine trials favored the treatment group, but only one significantly so (SMD of HAM-A range −0.19 to −0.42; low SOE). The two sertraline trials found effect sizes in the opposite direction, with one trial favoring sertraline and the other favoring placebo (insufficient SOE).”

Figure 24Standardized mean change from baseline in anxiety symptoms (HAM-A) for selective serotonin reuptake inhibitors compared with placebo

CI = confidence interval; HAM-A = Hamilton Anxiety Rating Scale; SMD = standardized mean difference; SSRI = selective serotonin reuptake inhibitor.

From: Results

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.
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