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Skelly AC, Chou R, Dettori JR, et al. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2020 Apr. (Comparative Effectiveness Review, No. 227.)

Key Messages

Purpose of Review

To assess noninvasive nonpharmacological treatments for common chronic pain conditions.

Key Messages

  • Interventions that improved function and/or pain for ≥1 month:
    • Low back pain: Exercise, psychological therapy, spinal manipulation, low-level laser therapy, massage, mindfulness-based stress reduction, yoga, acupuncture, multidisciplinary rehabilitation (MDR)
    • Neck pain: Exercise, low-level laser, mind-body practices, massage, acupuncture
    • Knee osteoarthritis: Exercise, cognitive behavioral therapy (CBT)
    • Hip osteoarthritis: Exercise, manual therapies
    • Fibromyalgia: Exercise, CBT, myofascial release massage, mindfulness practices, tai chi, qigong, acupuncture, MDR
    • Tension headache: Spinal manipulation
  • Some interventions did not improve function or pain.
  • Serious harms were not observed with the interventions.