This analytic framework is a model linking the key questions, evidence, and the population related to the clinical outcomes. Here, the population of interest is patients with osteoarthritis who are appropriate candidates for analgesic medications (intervention) and the clinical outcomes are improvement in osteoarthritis symptoms. Another possible outcome is the adverse effects of these medications.

Figure 1Analytic framework

From: Methods

Cover of Analgesics for Osteoarthritis
Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet].
Comparative Effectiveness Reviews, No. 38.
Chou R, McDonagh MS, Nakamoto E, et al.
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