Appendix EEvidence Tables

Index of Studies by Key Question

Abbreviations used in the evidence tables

ACR

American College of Rheumatology

ADA

adalimumab

AEs

adverse events

AIDS

acquired immunodeficiency syndrome

AIMS

Arthritis Impact Measurement Scales

ANA

anakinra

ARA

American Rheumatism Association criteria (pre-1987)

AS

ankylosing spondylitis

ASHI

Arthritis-Specific Health Index (Medical Outcomes Study Short Form SF-36 Arthritis-specific Health Index)

AUC

area under the curve

BUD

budesonide

Ccs

corticosteroids

CFS

chronic fatigue syndrome

CHF

coronary heart failure

Cm

centimeters

Combo

combination therapy

CI

confidence interval

CHD

coronary heart disease

COPD

Chronic Obstructive Pulmonary Disease

CRP

C-reactive protein

CVD

cardiovascular disease

CXT

cyclophosamide

CYP

cyclosporine

Ds

days

DM

diabetes mellitus

DAS

Disease Activity Score

DMARD

disease modifying antirheumatic drug

D-HAQ

Dutch version of the Health Assessment Questionnaire (HAQ)

EQ-5D–

Quality of Life Questionnaire

ESR

erythrocyte sedimentation rate

ETA

etanercept

EULAR

European League against Rheumatism

EuroQol EQ-5D

European Quality of Life Questionnaire

EuroQOL VAS

European Quality of Life Visual Analogue Scale

GI

gastrointestinal

HAQ

Health Assessment Questionnaire

HAQ-DI

Disability Index of the Heath Assessment Questionnaire (HAQ)

HIV

Human immunodeficiency virus

HLA-DR4

Human immune-response, D-related antigen encoded by the D locus on chromosome 6

HR

hazard ratio

HRQOL

health related quality of life

ICD

International Classification of Diseases

INF

infliximab

ISRs

injection site reactions

ITT

intention to treat

JRA

juvenile rheumatoid arthritis

HCQ

hydroxychloroquine

JSN

joint space narrowing

LEF

leflunomide

MTX

methotrexate

Mg

milligrams

mSharp Scale

Modified Sharp Method for Scoring Radiographs

mos

months

MHAQ

Modified Health Assessment Questionnaire

NSAIDs

non-steroidal anti-inflammatory drugs

NSFHS

National Survey of Functional Health Status

NA

not applicable

NMSC

non-melanoma skin cancer

NR

not reported

NS

not significant

NYHA

New York Heart Association

OA

osteoarthritis

OR

odds ratio

OMERACT

Outcome Measures in Rheumatology Clinical Trials

PASI

Psoriasis Area and Severity Index

PNL

prednisolone

PRED

prednisone

PsA

psoriatic arthritis

PsARC

Psoriatic Arthritis Response Scale

Pt

patient

PY

person-year

QOL

quality of life

RCT

randomized controlled trial

RAI

Ritchie Articular Index

RA

rheumatoid arthritis

RDS

radiological damage score

RF

rheumatoid factor

RIT

rituximab

RR

risk ratio

SAEs

serious adverse events

SAARDs

slow-acting anti-rheumatic drugs

SCC

squamous cell carcinoma

SD

standard deviation

SF-36

Medical Outcomes Study Short Form 36 Health Survey

SJC

swollen joint count

SHS

Sharp/van der Heijde Method (SHS) for Scoring Radiographs

SIR

standardized incidence ratio

SLE

Systemic Lupus Erythematosus

SMR

standardized morbidity ratio

SSZ

sulfasalazine

SSTG

South Swedish Arthritis Treatment Group

TB

Tuberculosis

TIM

targeted immune modulator

TJC

tender joint count

TNF

tumor necrosis factor

Txt

treatment

URTI

upper respiratory tract infection

UTI

urinary tract infection

vs.

versus

yrs

years

w/

with

w/in

with in

w/o

with out

Evidence Tables

Evidence Table 1. Randomized controlled trials and observational studies (MS Word, 1.0M)

Evidence Table 2. Systematic reviews and meta-analyses (MS Word, 159K)

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81.

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