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Butler M, Olson A, Drekonja D, et al. Early Diagnosis, Prevention, and Treatment of Clostridium difficile: Update [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2016 Mar. (Comparative Effectiveness Reviews, No. 172.)

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Early Diagnosis, Prevention, and Treatment of Clostridium difficile: Update [Internet].

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Appendix HStrength of Evidence

The Strength of Evidence approach relies on a technique called structured implicit judgment. This technique has reviewers rate the quality of individual components and then use their judgment to produce an overall rating that takes all the components into account. For Strength of Evidence, the domains are reported out as categorical, but in fact represent concepts that should be viewed as a continuum. The final overall assessment should be consistent with domains but convey a final, global assessment. Thus, two outcomes can have two different overall assessments (that is, either insufficient or low, or low or moderate, or moderate or high) when the domains are coded identically.

Appendix Table H1. Strength of evidence assessments

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