The analytic framework depicts the impact of both screening and treatment for OAG. It depicts the Key Questions (KQs) within the context of the inclusion criteria described in the following sections. The figure depicts how screening-based programs, which may incorporate treatment when indicated, may reduce visual impairment (S: KQ1) and/or improve patient reported outcomes (S: KQ2), reduce intraocular pressure (S: KQ4) and possibly slow the progression of optic nerve damage and/or visual field loss (S: KQ5). The figure also incorporates the potential predictive value of screening-based programs to detect OAG and OAG suspects (S: KQ3). Finally, the potential for harms of screening (S: KQ6) are illustrated in the framework.

Figure 1Analytic framework for screening and treatment for open-angle glaucoma

KQ = Key Question; T = Key questions for the Comparative Effectiveness of Treatment for Glaucoma; S = Key questions for the Comparative Effectiveness of Screening for Glaucoma

From: Methods

Cover of Screening for Glaucoma: Comparative Effectiveness
Screening for Glaucoma: Comparative Effectiveness [Internet].
Comparative Effectiveness Reviews, No. 59.
Ervin AM, Boland MV, Myrowitz EH, et al.
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