Literature Search Strategy
A limited literature search was conducted on key resources including PubMed, The Cochrane Library (2014, Issue 6), University of York Centre for Reviews and Dissemination (CRD) databases, Canadian and major international health technology agencies, as well as a focused Internet search. Methodological filters were applied to limit retrieval to health technology assessments, systematic reviews, meta-analyses, randomized controlled trials and non-randomized studies containing safety data. Where possible, retrieval was limited to the human population. The search was also limited to English language documents published between January 1, 2004 and May 30, 2014.
Rapid Response reports are organized so that the evidence for each research question is presented separately.
Selection Criteria and Methods
One reviewer screened citations and selected studies. In the first level of screening, titles and abstracts were reviewed for relevance. Full texts of any relevant titles or abstracts were retrieved, and assessed for inclusion. The final article selection was based on the inclusion criteria presented in Table 1.
Table 1
Selection Criteria.
Exclusion Criteria
Articles were excluded if they did not meet the selection criteria in Table 1, if they were published prior to January 2004, if they were duplicate publications of the same study, or if they were referenced in a selected systematic review.
Critical Appraisal of Individual Studies
The quality of the included RCTs was assessed using the Scottish Intercollegiate Guidelines Network (SIGN50) methodology checklist.5 Numeric scores were not calculated. Instead, the strengths and limitations of the study are summarized and presented.
Publication Details
Copyright
Copyright: This report contains CADTH copyright material and may contain material in which a third party owns copyright. This report may be used for the purposes of research or private study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner.
Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions.
Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial- NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/
Publisher
Canadian Agency for Drugs and Technologies in Health, Ottawa (ON)
NLM Citation
Ketorolac for Pain Management: A Review of the Clinical Evidence [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Jun 30. METHODS.