APPENDIX 2Characteristics of Included Publications
Table A1Characteristics of Included Clinical Studies
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First Author,
Publication
Year, Country,
Study Name | Study Design | Patient Characteristics | Intervention(s) | Comparator(s) | Clinical Outcomes |
|---|
Haas,11 2014
The USA | A retrospective study | Adult and pediatric patients including those receiving specialized services for trauma, burn, neurosurgery, cardiothoracic surgery, transplant, and oncology. | Pulsed xenon UVD following discharge cleaning of contact precautions rooms and other high-risk areas | Standard cleaning/disinfection before UVC | Incidence rates of hospital acquired MDROs plus C. difficile before and during the UVD |
Lazary,1 2014
Israel | A Cohort study over two parallel periods; one before (period A) and the other after (period B) | Two analogous patient cohorts with severe head injuries and in long-term care for head injury. | Biocidal copper oxide impregnated linens | Non-biocidal linens | HAI rates in a long-term care ward |
Ryan,3 2011,
The USA | Prospective pre- and post-intervention design | NICU patients who had an endotracheal tube in place | eUVGI applied to central coil components of HVAC | Standard cleaning/disinfection before eUVGI | Decreased pathogens in the NICU air and surfaces, decreased tracheal colonization and VAP prevalence in intubated NICU patients |
Boyce,5 2008
The USA | A prospective before-after intervention study | Patients on admission at a university-affiliated hospital. | HPV decontamination | Standard cleaning with detergent, and disinfection with sodium hypochlorite solution (1,000 ppm) where applicable | Reduced environmental contamination and nosocomial transmission of C. difficile measured by changes in CDAD |
CDAD = Clostridium difficile-associated disease; eUVGI = enhanced ultraviolet germicidal irradiation; HAI = healthcare-associated infections; HPV = hydrogen peroxide vapour; HVAC = heating ventilation and air conditioning; MDRO = Multiple-drug-resistant organisms; NICU = neonatal intensive care unit; USA = United States of America; UV = ultraviolet; UVD = UV disinfection; VAP = ventilator-associated pneumonia; VHP = vaporized hydrogen peroxide; VRE = vancomycin-resistant Enterococcus;
