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Heller S, Lawton J, Amiel S, et al. Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes. Southampton (UK): NIHR Journals Library; 2014 Dec. (Programme Grants for Applied Research, No. 2.5.)

Cover of Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes

Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes.

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List of abbreviations

BGAT

Blood Glucose Awareness Training

BMI

body mass index

CGM

continuous glucose monitoring

CI

confidence interval

CICS

Corporate Information and Computing Services

CIDS

Confidence in Diabetes Self-Care

CP

carbohydrate portion

CSII

continuous subcutaneous insulin infusion

CVD

cardiovascular disease

DAFNE

Dose Adjustment For Normal Eating

DAFNE 5 × 1 day

randomised controlled trial of DAFNE training delivered for 5 continuous days over 1 week vs. DAFNE training delivered for 1 day per week for 5 continuous weeks

DAFNE-HART

Dose Adjustment For Normal Eating Hypoglycaemia Awareness Restoration Training

DCCT

Diabetes Control and Complications Trial

df

degrees of freedom

DIG-AMI

Diabetes mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction

DKA

diabetic ketoacidosis

DSQOLS

Diabetes-Specific Quality of Life Scale

DUAG

Dose Adjustment For Normal Eating Users Action Group

DUG

Dose Adjustment For Normal Eating User Group

EDIC

Epidemiology of Diabetes Interventions and Complications

eGFR

estimated glomerular filtration rate

EQ-5D

European Quality of Life-5 Dimensions

EQ VAS

European Quality Visual Analogue Scale

ESRD

end-stage renal disease

FIIT

flexible intensive insulin therapy

GEE

generalised estimating equation

GP

general practitioner

HADS

Hospital Anxiety and Depression Scale

HADS-A

Hospital Anxiety and Depression Scale – anxiety

HADS-D

Hospital Anxiety and Depression Scale – depression

HbA1c

glycated haemoglobin

HDL

high-density lipoprotein

HFS-W

Hypoglycaemia Fear Survey Worry subscale

HTA

Health Technology Assessment

ICC

intracluster correlation coefficient

ICER

Incremental cost-effectiveness ratio

ITT

intention to treat

ITTP

Insulin Treatment and Training Programme

LDL

low-density lipoprotein

MDI

multidose injection (insulin)

MI

myocardial infarction

NICE

National Institute for Health and Care Excellence

NIHR

National Institute for Health Research

NPH

neutral protamine Hagedorn

NTCRN

North Trent Cancer Research Network

OLS

ordinary least square

PAID

Problem Areas in Diabetes

PMD

Personal Models of Diabetes

PPI

patient and public involvement

PROM

patient-reported outcome measure

PSA

probabilistic sensitivity analysis

QALY

quality-adjusted life-year

QoL

quality of life

RCT

randomised controlled trial

RE-AIM

Reach, Efficacy, Adoption Implementation, Maintenance

REPOSE

Relative Effectiveness of Pumps Over MDI and Structured Education

RfPB

Research for Patient Benefit

RQ

research question

ScHARR

School of Health and Related Research

SCI-R

Self-Care Inventory – Revised

SD

standard deviation

SF-6D

Short Form questionnaire-6 Dimensions

SF-12

Short Form questionnaire-12 items

SF-36

Short Form questionnaire-36 items

SMBG

self-monitoring of blood glucose

SMQ

self-management questionnaire

SSQ6

6-item Social Support Questionnaire

UKPDS

UK Prospective Diabetes Study

WESDR

Wisconsin Epidemiology Study of Diabetic Retinopathy

WHO-5

World Health Organization 5-item questionnaire

WTE

whole-time equivalent

Copyright © Queen’s Printer and Controller of HMSO 2014. This work was produced by Heller et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK263956

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