1Z3H


Conserved Protein Domain Family
Cse1

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pfam08506: Cse1 
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Cse1
This domain is present in Cse1 nuclear export receptor proteins. Cse1 mediates the nuclear export of importin alpha. This domain contains HEAT repeats.
Statistics
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PSSM-Id: 430038
Aligned: 13 rows
Threshold Bit Score: 537.272
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1Z3H_B    150 IFKRWRPLFRSDELFLEIKLVLDVFTAPFLNLLKTVDEQITA--NE-NNKASLNILFDVLLVLIKLYYDFNCQDIPEFFE 226  baker's yeast
O13671    149 IFKRWRPLFRSDALFLEIKYVLDRFCEPFLALFVQTNNLLRN--GP-QDAESLNSLFQVILLECKLFYDLNCQDIPEFFE 225  Schizosaccharomyc...
Q9ZPY7    162 IFKKFSYEYRTDALFVDLKYCLDNFAAPLTEIFLKTSSLIDSaaSSgGSPPILKPLFESQRLCCTIFYSLNFQDLPEFFE 241  thale cress
Q965V4    150 IFRKFRFESKSAELWKELKKCLLSTQEPLTLLLRNMMEVGQR--KDqLGADEIAQWLRVLLLIAKVYHSLCSQEIPEYFE 227  Caenorhabditis el...
Q9XZU1    159 LFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLLQAKMQLTKV--HE-NNAGALKVIYGSLVLVNKVFFSLNSQDLPEFFE 235  fruit fly
Q5AYN9    150 IFKRWRPLFRSDDLYIEINHVLERFGTPFLTLFQGLDTYLET--NK-SNKDQLTQGFTQLNLMVKLVYDLSCHDLPPMFE 226  Aspergillus nidulans
XP_960866 151 IFARWRPLFSSNALNIEVNHVVNTFGDSFIQMLGVADQQIEA--NK-TNEKALKGWLETMSLLTRIFFDLSCQDLPPIIE 227 
Q6C6Q8    150 IFKKWRPLFSSDDLNREILLVLNQFTEPYKQLCEEVDRQIEA--NS-NNKAQLDILFRVQFNIFKIFFDLNCQDIPAFFE 226  Yarrowia lipolytica
Q6BJX9    152 IFKRWRPLFRSDELFLEIKLVLDKFAEPFLTLLNKLDQLISEalSK-HDKASLNIYFENLLLLIQIYYDLNSQDIPEFFE 230  Debaryomyces hans...
Q6CYF2    150 ICKRWRPLFRSDELFLEIQMVLDKFAVPFLTMLQTVDKQIDE--YS-SDKARMVILFDVLLLLVKLYYDLNCQDIPAFFE 226  Kluyveromyces lactis
Q753N9    164 IFKRWRPLFTSDALYLEIKLVLEKFAGPFLHLLQTVDEQISA--NR-ADEAKLRLLFDVLLVLVKLYYDLNCQDIPEFFE 240  Eremothecium goss...
Q7QE09    159 LFKRYRYEFKSQELWEEIKYVLDKMAKPLTDLLQATLGLAEA--HA-GNKEALSVIYNSLVLVCKVFFSLNSQDLPEFFE 235  Anopheles gambiae...
Q6FRK6    150 IFKRWRPLFRTNELFLEIKLVLDKFTEPFLNLMKSVDEQITH--KK-DDKASLELLFDVLLLLVKLYYDFNCQDIPEFFE 226  [Candida] glabrata
1Z3H_B    227 DNIQVGMGIFHKYLSYSNPLLEdpDETEHASVLIKVKSSIQELVQLYTTRYEDVFgPMINEFIQITWNLLTS-ISNQPKY 305  baker's yeast
O13671    226 DHMSEFMTAFLNYFTYTNPSLE--GDEGETNVLIKVKASICEIVELYTLRYEEVF-TMLYDFVNVTWTLLTT-LTPDEKY 301  Schizosaccharomyc...
Q9ZPY7    242 DHMKEWMGEFKKYLSSNYPALE--STEEGLTLVDDLRAAICENINHYIEKNEEEFqGFLNEFASVVWTLLRD-VSKSPSR 318  thale cress
Q965V4    228 DHLKDWMPHFLHLVQIDAPTQT--SNSGEPTTLDELKHEICEIFTLYSQRYEEEIsEFVPDIILAVWNLLKS-TGPDTRY 304  Caenorhabditis el...
Q9XZU1    236 DNINTWMGAFIQQLAADVPSLRt-ADDEDAGVLEHLRAQVCENICLYAKKYDEEFkPFMEQFVTAVWELLVK-TSLHTKY 313  fruit fly
Q5AYN9    227 ENMSGLAQILLKYLTYDNQLLHt-DDDAESGQLEYVRAGIFEVLTLYVQKYGDEFqPYIQQFVESSWNFLTT-IGQETKY 304  Aspergillus nidulans
XP_960866 228 TNLQPITMVLHKYLSYANPLFD--DEEDEATPIEILKSDICDALHLFVTKYDDDFgGYVQDFTSNVWNVLSS-VGPQKRY 304 
Q6C6Q8    227 DNLDYFMNLLKKYLCYTNPLLEdpDEDDEAGILEKVKASICDAIQLYSLRYEEFFgTYLNGFVETVWNLLTN-TSTQPKY 305  Yarrowia lipolytica
Q6BJX9    231 DHMMNGMEIMHKYLVLETPLLTdqDSDDEIDVLIKTKTSIVELVSLYVSRYADVFePLIENFITTIWKLINSyVTKQQKF 310  Debaryomyces hans...
Q6CYF2    227 DNMSVGMSIMHKYLNYQNPLLEdnTEDEEASVLSKVKASIAELIQLYISRYQEEFdPMVDNFIQTTWNLLVS-LTPQPKY 305  Kluyveromyces lactis
Q753N9    241 DNMQVGMGIMHKYLAYDNPLLEdeTEDEEASVVTKVKSSIAELVQLYTSRYEDVFgPMVEQFIQTTWNLLVS-LTCQPKY 319  Eremothecium goss...
Q7QE09    236 DNMETWMKAFHGLLTVDVPCLKt-DDDEDAGVLEHLRSQICENLCMYALKYDEEFsPYMPQFVTAVWELLVK-SHIHTKY 313  Anopheles gambiae...
Q6FRK6    227 DHIREGMGMWHRYLSYENPLLEdnFDTETASTLIKVKTSIQELVQLYTTRYEEFFePMINEFIQITWSLLVS-TPNQPKY 305  [Candida] glabrata
1Z3H_B    306 DILVSKSLSFLTAVTRIPKYFEIFNNESAMNNITEQIILPNVTLREEDVELFEDDPIEYIRRDLEGSDTDTRRRACTDFL 385  baker's yeast
O13671    302 DGLVGKAMAFLTSVIRIRKHAEFFQQDQVLQQFIELVVLPNICLRESDEELFEDDPLEYVRRDLEGSNSDSRARSAIVLV 381  Schizosaccharomyc...
Q9ZPY7    319 DQLATTAIKFLTSVSTSVHHA-LFAGDNVIKEICQSIVIPNVSLRVEDEEIFEMNYIEFIRRDMEGSDVDTRRRIACELL 397  thale cress
Q965V4    305 DTMVCAALEFLSMVSQRQYYEGHFTGEGVLKTLAENVCVQNLLLRQQDMELFEDEPLDYMKRDIEGTDVGTRRRGAIDLA 384  Caenorhabditis el...
Q9XZU1    314 DSLVSHALQFLSVVADRQHYQSIFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLV 393  fruit fly
Q5AYN9    305 DILVSRALKFLTSIAGMPQHAQIFQAESTLAQVIEKVVLPNVSLRESDEELFEDEPIEFIRRDLEGSDSDTRRRAATDFL 384  Aspergillus nidulans
XP_960866 305 DVLVSKALHFLTAVASVHRHAQIFNNEEILGTIVEKVILPNVTLRESDIELFEDEPIEFIRRDLEGSDTDSRRKAATDFL 384 
Q6C6Q8    306 DILVSRALTFLTSVAKVPRHTNMFSSPEVLKQLIEKIVVPNMSLRESDEELFEDDPLEYIRRDLEGSDSDTRRRAATDFL 385  Yarrowia lipolytica
Q6BJX9    311 DLLVVKALSFLTSVTKMAKYQPLFDNETSLKEIIEKIILPNIYFREIDEELFEDEPINFVRSDLEGSDFDSRRKSATDFL 390  Debaryomyces hans...
Q6CYF2    306 DILVSKCMTFVTAVARVPKYFELFNTESAMNSIIKEIVLPNVTLRESDEELFEDDPIEYIRRDLEGSDSDTRRRACTDFL 385  Kluyveromyces lactis
Q753N9    320 DILVSKCLSFMTAVARIPRYFNLFNNEAAINSVTEKIILPNVTLRDSDVELFEDDPIEYIRRDLEGSDSDTRRRACTDFL 399  Eremothecium goss...
Q7QE09    314 DALVSNALRFLSTVAERTHYRHLFEDPNVLASICEKVIIPNMDFRVSDEELFEDNPEEYIRRDIEGSDVETRRRAACDLV 393  Anopheles gambiae...
Q6FRK6    306 DILVSKSLSFLTAVARIPKYFEVFNTDSAMHSITEQIILPNYTLREEDVELFEDDPMEYIRRDMEGSDSDTRRRATADFL 385  [Candida] glabrata
1Z3H_B    386 KELKEKNEVLVTNIFLAHMKGFVDQYMSDPSKNWKFKDLYIYLFTALAINGNITNA-GVSSTNNLLNVVDFFTKEIAPDL 464  baker's yeast
O13671    382 RGLLDHFDQKITSVVSTHINANLQQFSTNPSLEWNKKYVALQLFSAIAIKGQSTRL-GVTSINLMVDVVAFFENNIKPDL 460  Schizosaccharomyc...
Q9ZPY7    398 KGLATNYKTQVTEVVSLEIQRLLSSFSANPSANWKDKDCAIYLVVSLSTKKAG----GASVSTDLIDVQNFFANIILPEL 473  thale cress
Q965V4    385 RGLCRRFEAQMLPCLGEIVQNLLG------SGDWIKIDIVYSLITAIAVKTETAKS-GVTATNPLVDINDFFITQVATHL 457  Caenorhabditis el...
Q9XZU1    394 KTLSINFEQKIFGIFGQYLERLLTKYKENPATNWRSKDTAIYLVTSWASRGGTQKH-GITQTSELVPLPEFCAQQIIPEL 472  fruit fly
Q5AYN9    385 KQLNANFEASVTKAVLQYIEHYLNEYGKSPQLNWKAKDTATYLFIAIAAKGVATAThGVTTTNSLISITDFFQKNLAADL 464  Aspergillus nidulans
XP_960866 385 RKLLDDFEALVTQVVSKYINHYLEM----GKTDWKAKDTAVYLFLAIAAKGAVTAAqGVKTVNSFVNVIDFFQQHIAADL 460 
Q6C6Q8    386 RELNDKAESSVTKVALEYVEQFLNLYKQDPASNWKAKDTAIHLYSSIAAKGAVTSS-GVTSINLTVDILSFFSENIAPDL 464  Yarrowia lipolytica
Q6BJX9    391 RELKEVNTGLLTNTVMTYVNQFLS-----SQSDWKNKDIAIYLFSSLAAKGSVTNV-GVTSTNVLVDVVKFFSDNIANDL 464  Debaryomyces hans...
Q6CYF2    386 KELKEKNESLVTNVVMVHIKSFFEEYNNNQILNWKHKDLCMYLFTSLAINGKVTNA-GVTSTNVMLDVVEFFKSDVVPDL 464  Kluyveromyces lactis
Q753N9    400 KELKEKNESLLTNIVLSHIKKFFEKYHAHPQENWKYKDLCVYLFTSLAVKGNVTSS-GVSSTNAMLDVVDFFTKEVMSDL 478  Eremothecium goss...
Q7QE09    394 KSLLQKFEAKIVEIFGQYLQVLLAKYAENPAANWKAKDTAIYLVTSMASKGQTQKL-GVTQTSELVPLPQFTQQQIIPEL 472  Anopheles gambiae...
Q6FRK6    386 GELKEKNENLVTSIILEHVKKFHDQYSTNPQEFWKYKDLYINLFTSLAVKGNITNS-GVSSTNPLVNVIDFFTIQILPDL 464  [Candida] glabrata
1Z3H_B    465 T-SNNIPHIILRVDAIKYIYTFRNQLTKAQLIELMPILATFLQTDEYVVYTYAAITI 520  baker's yeast
O13671    461 LqPAGVIHPMVLAEDIKYVFTFRNQLNSQQLIDIFPTILRFLEMPSFVVYTYAAIAL 517  Schizosaccharomyces pombe 972h-
Q9ZPY7    474 QsRDVNSFPMLKAGSLKFLTMFRSHIPKPFAMQLFPELVRFLKAESNVVHSYAASCI 530  thale cress
Q965V4    458 N-ADVNQTPILKADALKFAVTFRKQLAPEHLMTAIKSADALLSSNTPILHKYAAYAI 513  Caenorhabditis elegans
Q9XZU1    473 ErPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSVVHSYAACSV 529  fruit fly
Q5AYN9    465 V-SGDGVHPILKVDAIKYLYLFRSLITKEQWQEVFPLLVNHLGSSNFVVYTYAAIAV 520  Aspergillus nidulans
XP_960866 461 V--ATGGEPIPKVDAIKFLYNFRSQLSKEQWGGAINPLIQNLASPNYVVYTYAATTL 515 
Q6C6Q8    465 M--NDSANPILKVDAIKYIYTFRNQLSRDHLIQVFPVLMNHLLSTNYVVCTYSAVTV 519  Yarrowia lipolytica
Q6BJX9    465 MnTNHSTNPILKTDAIKYIFTFRNQLTKDQLLTTFPLLINHLQDSNTVVYTYSSITI 521  Debaryomyces hansenii
Q6CYF2    465 L--NQQAHPILRVDAIKYVYVFRNQLSKEQLIEILPVMAKFLQDKEYVVYTYAAITI 519  Kluyveromyces lactis
Q753N9    479 N--GHVPHVILRVDAIKYIHTFRNQFTKEHLVQILPVMANFLQDSEYVVYTYAAVTI 533  Eremothecium gossypii
Q7QE09    473 ErADVNQLPVLKADALKFIMTFRTILGPQIIVATMPLVSKHLGAASVVVHTYAACAI 529  Anopheles gambiae str. PEST
Q6FRK6    465 M-AGSLPHPILRVDAIKFVYNFRNQLNKQQLIEILPILANFLLNGEYLVFTYAAITI 520  [Candida] glabrata
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