Conserved Protein Domain Family
KPBB_C

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pfam19292: KPBB_C 
Phosphorylase b kinase C-terminal domain
This entry represents the C-terminal domain found in Phosphorylase b kinase regulatory alpha and beta subunits, which control the catalytic activity of the Phosphorylase kinase catalytic gamma subunit. this domain has been proposed as the second calcineurin B-like (CBL-2) domain containing a gamma subunit-binding site.
Statistics
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PSSM-Id: 437124
Aligned: 57 rows
Threshold Bit Score: 307.935
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KDB53751                 865 REHGLTQAEGFDFLLSLSPQAILRRLREVIAHEQEMGRNLLRLQSLHGRVSrdG-GPLARVRFPAsADp-VLdDASGGWL 942 
WP_002710230             829 PATRLSISQAMDELMNMAPHRVARAVRDVLEHYQDAHDSLTQLERMHVASD--S-GGMVTVQFDSsMNp-EL-TYSADWH 903  Th...
WP_065089452             830 SAGQPAISDTLDVLMDMEPHEFAGALRDVLQHYHAAQDAMQQLERMHVSVD--S-SGMTRVRFDAgIDp-DN-SDAGDWH 904  Ac...
OQK18180                 835 RQQKCNLGEAFDALVALPPHTIELKVKETLADYQNSESQLNMSESLRYEGQ--I-KNLDSARFSEqIDpkDR-GRAGDWH 910 
ESS73436                 836 GDLHYTNDQAFNEIMSLSPYELSKKVHQTIVDYSNSEIKTGFLEKLNYVGD--F-LGLNKAIFAKaAMptDF-ERFENWY 911 
CCE22395                 834 KDSNCTLDQAYNEVLTLPPYQLMQKVRETLEDFTNTQYQFERVETLNYVGQ--C-QELTCARFSPkMDpeNF-GEAEDWY 909 
WP_006892613             837 ESGCGTLDQAFNAILSLPPYQLSGNVKETLEDYSNTEDQLGLAETLHYEGD--C-RELTGARFPKnMDpkDH-SEIDDWY 912  Me...
SJM96533                 847 ESDCGAPDLTFNEILSLPPYQLFRKVTETLEDYSNTEDQLELSEALHYEGD--C-RELTRARFSKnMDanDR-GDVDGWY 922 
PRJNA391059:CEK71_11080  837 RETGGTLDQAFNDILFLSPYQLSQKVRETLADYSNTESQLSQVEALNHEGD--C-ADLGQARFSKaMDaqDH-VGNADWY 912 
34:YC6258_02928          835 SEQALAPSDAFELLCSLSPYDLFDRVRKVLENYEVSVQRLIAQESLPATHHg-PiCEVHFDSKDD--P--LL-GEENDWK 908 
KDB53751                 943 AWREVRGVLTRLPEDFHARVWEVLRHFPGLVIGDQLDSRNRLDSHLARADMTASERGFALQVDDLLNKIHAPEYRQLTIE 1022
WP_002710230             904 EWRSNQGKLGRYSDSFFEGVWDIVNQTHGLVIGDQWNTKLRLAHR-LCADMTRGEKLFRDRVTHILHKTPAPDSLKLYGE 982  Th...
WP_065089452             905 QWRAIQGSLGLYPEDYFEGVWDIVNQSRGLVIGDQWNPKRRLDHK-LCADMTRGERQFQDRVEHILNKTPAPDARQLYTE 983  Ac...
OQK18180                 911 EWREQQGSIGRQTESFFADVWEVLHHCKGLIISEKLNKQRRLDSEHILAEMTDKEKSFVLLINHRLDKVQSPDYRQLTVE 990 
ESS73436                 912 QWREMRGSIGKENDSFFAHVWDLLHRCKGVVIGDRLNSKRRLDSEIVLAHMTAGEQSFKLHVNHLLNKIQLPVHRQLTVE 991 
CCE22395                 910 NWRERRGSLGRESESFFTGVWDILHHCQGLMIGDKLSSKRRLDSETTLAQMTSGEQSFKLHVNHLLNKIQAPVYRQLTVE 989 
WP_006892613             913 GWREQQGSVGRENDVFFASVWDILHHCKGLAIGDKLNSKNRLDSENTLSQSTAGEQSFKLHVNHLLNKIQAPVYRQLTVE 992  Me...
SJM96533                 923 AWREQQGSVGRENSVFFASVWDILHHCQGLTIGEKFNAKNRLDSETTLSQSTAGEQSFQLHVSHLLNKIQAPVYRQLTVE 1002
PRJNA391059:CEK71_11080  913 DWRERQGSVGRENDAFFASVWTILHHCSGLMIGEKLNSKRRLDSEIILSQMTSGEQSFKIHVSHLLNKIQSPVYRQLTVE 992 
34:YC6258_02928          909 KWREVQGLIPRFHDNFFSDLWNLLNHCHGIVLGDRFDSRTRMDSDIALNSMTGGEAQFANLIEKMLIRISTNSYRQMTIE 988 
KDB53751                1023 ALIAVSDIARANPDLAADGLLVMDVLIGIAVRLGWEQSLPARArgegadddtppLDYNEHKAAAWQGFYALPPHRVATLV 1102
WP_002710230             983 ALQVLMLVMRNNPQLRIEDTVYLDVLIGHAVRLAWLQRQPQAA-----------EDYDQYRADAWKAFYLSPPSDVANHI 1051 Th...
WP_065089452             984 ALRVLMLVMWKNPGLRIDDTLYLDVIIGHAVRLAWEQAHPDQQ-----------SLYDEQRATAWKDFYLSPPSAVANHV 1052 Ac...
OQK18180                 991 TLHALASIFRDNPDLQVEDTLMTDTLIYHAVRLTWLDKHPERE-----------AQYELDHALSWQGFYQLPPHEVANGI 1059
ESS73436                 992 VLTVIATVFHDNPTLRIDDTLSTDSLIEHAAKIASQKWHRNAQ-----------KNDEQDEESVWHYFYHLPPHKVANCY 1060
CCE22395                 990 ALNAMAFVFRDNPSIRIEDTLVTDIIIGHAVRLCWLKLHPEAK-----------DNYKEVVSLAWQAFYQLPPHQVANGM 1058
WP_006892613             993 ALKAMASIFRETPSLHIDDTLLTDIIIGHAVRVSWLQAHPESK-----------DNYEECVSLAWQDFYRLPPHKVANGI 1061 Me...
SJM96533                1003 TLKAIAFIFRENPALHIDDTLVTDTLIDHAVRINWLQSNPEHK-----------DNIDDSTLLAWQDFYHAPPHQIANGI 1071
PRJNA391059:CEK71_11080  993 AIKAIASIFHTNSVYIND-TLVTDVIIGHAVRICWLQAHPLHQ-----------DHYEEHVSIAWQAFYQLPPHRVANGI 1060
34:YC6258_02928          989 VIQALCSLFKMNPDLRVPHLLVVEVILGHAVRLNWINQEDHDA-----------DQYNAERGKAWQEFYQLPPYRVALAV 1057
KDB53751                1103 MDALAFLMTPE-PAEA 1117
WP_002710230            1052 MTALVYLLNSDaKEAV 1067 Thiothrix nivea
WP_065089452            1053 MDALAFLLNGSaRQSA 1068 Acidihalobacter prosperus
OQK18180                1060 IDGLKYLLATN-NEIP 1074
ESS73436                1061 VEALTHLLDNT-PQDF 1075
CCE22395                1059 LDALIYLLENN-NQTK 1073
WP_006892613            1062 LDALIYLLNNN-ERAT 1076 Methylobacter tundripaludum
SJM96533                1072 LDALIHLLNNN-DRSS 1086
PRJNA391059:CEK71_11080 1061 LDALVHLLNNN--SLP 1074
34:YC6258_02928         1058 QTSFEYLIRQNdHAQL 1073
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