Conserved Protein Domain Family
mycofact_glyco

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TIGR03965: mycofact_glyco 
mycofactocin system glycosyltransferase
Members of this protein family are putative glycosyltransferases, members of pfam00535 (glycosyl transferase family 2). Members appear mostly in the Actinobacteria, where they appear to be part of a system for converting a precursor peptide (TIGR03969) into a novel redox carrier designated mycofactocin. A radical SAM enzyme, TIGR03962, is a proposed to be a key maturase for mycofactocin.
Statistics
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PSSM-Id: 274884
Aligned: 8 rows
Threshold Bit Score: 431.491
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEN88361      50 IRLDPKVRTYSGGRVLIGGSPTRMLKLAPTAAAMIGDGF------------LEVVDQQSAAVARHLLDSGVANPRPMSTP 117 Rhodococcus ery...
EEP39645      28 LAPGVRLVERASGSWVALSDPLRVWRVRPAALRLLAECQagqtva-aaaaaAGLRPATALRLLERLAEQGAVYFEPLGVD 106 Sphaerobacter t...
WP_011558421  12 VQVDRRVKVLDEGAALLGGSPTRLLRLAPAAQTMLSGGR------------LEVHDATSAQLARTLLDATVAHPRPASGP 79  Mycobacterium
WP_012643085  27 LSPCLRVVQCGDAAWLIATRPLRLLRVQPRVVKLLEKLRvdpdvgrvvksfPDLRWETVISFLERLADEGLVRLVWSLPD 106 Thermomicrobium...
WP_011211600  12 VRIDPRVRAYSGNRILIGGTPARVLRLAPEAAEMIGDGY------------LEVTGPKSAVVARRLLDSGVANPRPRLLP 79  Nocardia farcinica
WP_009947178  11 VELDRSARLSRNGRLVFGGSPGRLLRLHPRAAELVKAGS------------FTVRDPASAALARALLDVGVVHPRPAADE 78  Saccharopolyspo...
WP_011208763  10 IVLDRSVHRFDRGRVLLGGSPMRLVRLSAAGARLLAGWVdg---------gPIGADEGSARLLRRLLDSGLVHPVAAPGS 80  Nocardia farcinica
WP_011566061 261 LRGGLSVRRGGGGHVLLSERPLAALRVGPEAARLLGRLGgngtaa-eaaaaSGLPLDRATALLEGFVRRRVVARSGGTLP 339 Rubrobacter xyl...
EEN88361     118 s-AADVTVVIPVKDNQAGVERLLPVL------KD-LTVIVVDDGSEVPVEPRRAC-PGTGTITVVRHESARGPSAARNSG 188 Rhodococcus ery...
EEP39645     107 --PPTVSVVIPVRNRPKAILACLDALdplvypRDrLEVIVVDDASTDETPDIVARwTGSITVRLIRLPSRQGASACRNQG 184 Sphaerobacter t...
WP_011558421  80 s-HRDVTVVIPVRDNISGLQRLLASLr-------gLRVIVVDDGSATPIECTHMS-GVHCDVRVIRHDRSRGPAAARNTG 150 Mycobacterium
WP_012643085 107 emLPSVSVVIPVRNRPAQLSACLAALecldypRErLEILVVDDASSDDTVARAETwRNRLPLRVIRLPAPVGAAACRNHG 186 Thermomicrobium...
WP_011211600  80 s-TDDVTVVVPVHNNPEGLARMLAVLr-------gHHVIVVDDGSDQPVRIPETR-GTRCRVTVLRHDTAHGPAAARNAG 150 Nocardia farcinica
WP_009947178  79 e--RSVAIVVPVRDRQDMLARLLHAVrsdprtAG-VPIVVVDDGSRDAGATRAV--AAEHGAEVIRHDRSQGPASARNAG 153 Saccharopolyspo...
WP_011208763  81 rsPDEVTLVVPVKDNPAGLARLLAAt------TEfAHRVIVDDGSADAVPTA-----------TIRHPRPLGPAAARNAG 143 Nocardia farcinica
WP_011566061 340 srWPSATVVVPSRNRPRRARACAASLlaldypRDrLEIIFVDDASEPPLSRA----LAGLPVRVLRLERRAGQSAARNLG 415 Rubrobacter xyl...
EEN88361     189 LRSAQTRFVAFLDSDVIPRAGWLELMLGHFSDPGVALVAPRIVALd--P-YGTALARYENMRSSLDLGRKEAAVKSGSPV 265 Rhodococcus ery...
EEP39645     185 AAAARGEVLAFTDSDCLPAPGWLRDLTPELAIPGVVAAGGAVLPI---A-EDGWLQRYEAVRSPLWQGPARAVVRPRAPV 260 Sphaerobacter t...
WP_011558421 151 AAACSTDFVAFLDSDVLPRRGWLEALLGHFCDPAVALVAPRIVGLr--T-ADNPVARYEAVRSSLDLGHREAPVVPYGPV 227 Mycobacterium
WP_012643085 187 AELARGEILAFTDSDCRPHPRWLRELVPEFVRTGVVAVGGAVLPAd----DDSWLDRYEAVESPLTHGPEPARVRPRGAV 262 Thermomicrobium...
WP_011211600 151 LRAATTEFVAFLDSDVVPRSGWLEVMLGHFSDPEVALVAPRIVALd--A-ESNALARYEHTRSSLDLGRREAAVHSRGPV 227 Nocardia farcinica
WP_009947178 154 FHATTQEFVAFCDSDVVPEHGWLPPLLAQFDDPGVGLAAPRVVALp--QqRPTRIGSFEQTCSALDLGPDEAPIIPMSKV 231 Saccharopolyspo...
WP_011208763 144 WRRATTEFVAFVDSDVVPRPGWLDSALALFDDPRVAAVAPRVTSPpgtA-APTRVAAYEASHSSLDMGADPAVVRPLSRV 222 Nocardia farcinica
WP_011566061 416 LRAARGEVVAFTDDDCEVLPGWLRALAAPLCTPGVELAGGRVLSPp--P-A-GRLGAFEAARSPLDMGPEGGEVGPRGAV 491 Rubrobacter xyl...
EEN88361     266 AYVPSAAVIVRRDVALECNGFdESLEVAEDVDFCWRLQAAGWRLRYEPVAHVAHDHRVQFDKWFARRAFYGTGAAPLAAR 345 Rhodococcus ery...
EEP39645     261 SYLATCNLLVRRECFEAAGGF-AAIETGEDVDLIWRLCATGGRVHYRPDGVVRHDHRDRLWPFLRRRAAYAASEAELLRR 339 Sphaerobacter t...
WP_011558421 228 SYVPSAAIICRRRALDEVGGFdETMHSGEDVDLCWRLVEAGARLRYEPIALVAHDHRTDLGEWFLRKAFYGKSAAPLAVR 307 Mycobacterium
WP_012643085 263 PYLVTANLLVRRRALLEVGGF-ARIHPGEDVDLVWRLCERGGRVLYRPAGIVLHDHRDRLWPFLHRRAAYASSEVVLVQR 341 Thermomicrobium...
WP_011211600 228 SYVPSAALLVRRQALLAVGGFdESMRVAEDVDLCWRLERAGRRLRYEPAAHVAHDHRVAFRAWFGRKVFYGTGAAPLARR 307 Nocardia farcinica
WP_009947178 232 AYVPSAAIVLRRAAAPE--GFdEQLQVAEDVDLCMRLHEKGWRLRYVPTAQVAHDHRTALLPWAARRAFYGSGAAALAAR 309 Saccharopolyspo...
WP_011208763 223 GYVPTAALIVRRAALAELGGFdERLRFGEDVDVVWRLTDAGHLVRYHPAAVVTHRPRATLGSWLRQRYDYGTSAAPLSRR 302 Nocardia farcinica
WP_011566061 492 PYLPSCNLAGDRRALLRLGGFdEGMELGEDADLVWRAVRAGLGVRYEPSARVVHRHRTRLAALLARRADYGASEADLQRR 571 Rubrobacter xyl...
EEN88361     346 H-EGSVPPMAMSFsTLFA---CI-AAATL---------------TR----SGLASALGALLFTVYRLRK-MFTGLSQPTR 400 Rhodococcus ery...
EEP39645     340 H-PNNVRYLVVPLtLTAGlagAL-AAAASr-------------rAR----LAPLGVVPPLVDLALAVRRtRREGVPLAPA 400 Sphaerobacter t...
WP_011558421 308 H-PGKTAPLVISGwTLVVw--VL-MAMG----------------SC----IGYLASMLAAALTARRVAN-SLSSVRTEPR 362 Mycobacterium
WP_012643085 342 H-PHSRHRMTVPAaMLASi-gCG-IGAGRq--------------EG----LVMLAMLPLLADVLVAFQRiRRLRAPVSLG 400 Thermomicrobium...
WP_011211600 308 HgPAAVSPLSLPYwTALAa--VL-FATL----------------TR----WGLLGGLVALATALVRLRR-VFAGLDNPTR 363 Nocardia farcinica
WP_009947178 310 H-PGQVPPMHVTAwSLLAv--CL-ALTG----------------KP----AAVASATGLAAIAGTRLAR-RMPDADTPVR 364 Saccharopolyspo...
WP_011208763 303 H-PGRLACARVSAwHALSw-gALvVALGParpdraarglrraarSP----VLRGSAVVVPALVATALPArRLRGRGVPTA 376 Nocardia farcinica
WP_011566061 572 H-PEAARRMMVPAaGGLWl-gAL-GALGRs--------------RRgaalLAALSALLMGAEAGAKLLRaRRAGALLPLP 634 Rubrobacter xyl...
EEN88361     401 IAAILTAQGVVGGFWQLASAMCRHY-WPVTLLAVIASRR-----IRRLAVAAAVTEGLVDWYRHRE--Pg-----gLGPV 467 Rhodococcus ery...
EEP39645     401 SVARAVVRGYGAALYWGSVNLNRYYaIPALALSLAAGRRapgrgLRATVGLALIGTAVADWVRLRP--R-------LSLP 471 Sphaerobacter t...
WP_011558421 363 QVAAIAAQGLWSAALQLASAICRHY-WPIALLAALVSRR-----CRQAVLIAAVVDGVVDWAARRG--NtdddtkqVGLL 434 Mycobacterium
WP_012643085 401 ELVLAELRGMLVAFYWMGRTISRYYsWPVLVAGVIFRRRgfgrwLSVLVGASLLGTASVDYIRKRP--S-------LDPV 471 Thermomicrobium...
WP_011211600 364 IAALYLARGFFAGLWRIASAMCRHY-WPITLLAVLVSRR-----VRRIAVTMAVADGLADWFTHRDagG-------LDPV 430 Nocardia farcinica
WP_009947178 365 AAGLLTLAGLYSTALQLLRAGVRHH-WPIGLALVMKSRR-----ARWLLLGMSTVDGLVEWKKKAS--E-------LDPV 429 Saccharopolyspo...
WP_011208763 377 AALAVGAGGHLAAGLALADAVRRTW-WPV-LMGTRLGRR-----LVLLSLLPC----LVEALRGRR--G----------P 433 Nocardia farcinica
WP_011566061 635 AVAGAVLRQHGAELYHLGANVSRYY-GLPLGAAALLLRP-----LRLPALALLLPPPVVDHRRLRP--G-------LSPA 699 Rubrobacter xyl...
EEN88361     468 RYVFFKRADDIAYGAGLWRGAFDARDWAALKPRITK 503 Rhodococcus erythropolis SK121
EEP39645     472 RFAAAHMLDALAYNVGVLVGCARHRTLAPLRLQIVP 507 Sphaerobacter thermophilus DSM 20745
WP_011558421 435 TYVLLRRLDDIAYGLGLWTGVVRERHLGALKPQIRT 470 Mycobacterium
WP_012643085 472 RFLLAHLCDDLANNSGLLVGCLRSGTIRPLLVELSL 507 Thermomicrobium roseum
WP_011211600 431 RYLVYKRLDDLAYGTGLWVGAARARSLDALRPAFSR 466 Nocardia farcinica
WP_009947178 430 TFVVLRRIDDLAYGAGVWWGSVEHRTMAALVPKITG 465 Saccharopolyspora erythraea
WP_011208763 434 AWFAMRLADQAAYSLGVWAGCLRARTAAPLLPDLRV 469 Nocardia farcinica
WP_011566061 700 LFTLLWWLELAAYQLGVWRGCLRHRTprpllprllp 735 Rubrobacter xylanophilus
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