Conserved Protein Domain Family
Nsp2_AV
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pfam14755: Nsp2_AV 
Nsp2, transmembrane domain
This domain is found in Nsp2 protein of the RNA-arteriviruses, such as porcine arterivirus PRRSV and equine arterivirus EAV, which is a tetraspanning transmembrane protein. This domain resides adjacent to the peptidase C33 catalytic domain of Nsp2.
Links
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Statistics
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PSSM-Id: 373271
Aligned: 5 rows
Threshold Bit Score: 241.425
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ADI59013  361 GPPPAPVSASVLDHILEAATFGNVRVVATEEQQRPVPAPRARHSVSPP-GDVKDTATVPPVPKPRTKLAKPSPVQAPTPA 439 
ADI59063  101 GPPPAPVSASVLDHILEAATFGNVRVVATEEQQRPVPAPRTRLSASSP-GSAKDSPIVPPVPKPRTKLAASSSTQAPTPA 179 
Q6V7I2    361 GPPPAPVAASVLDHILEAATFGNVRVVAADEKQRPVPAPRTRPSPTPSeGAVSDPATTPPVPKPRTKLAKPSAPQAPTPA 440  Equine arteritis ...
P19811    361 GPPPAPVSAAVLDHILEAATFGNVRVVTPEGQPRPVPAPRVRPSANSS-GDVKDPAPVPPVPKPRTKLATPNPTQAPIPA 439  Equine arteritis ...
ADI59062  101 GPPPAPVSAAVLDHILEAATFGNVRVVTTEEQPRPVPAPRARPNAKSS-GDDKDPAPVPPVPKPRTKLVKPNPTQAPTPA 179 

ADI59013  440 PRTQPQDAvhsglPKPEPPTGTAAAPASAPRWRVAKTVYSSAERIRTELIHRAQSIGDSLVQALPLKAPAVQRY 513 
ADI59063  180 PRTRFQDV-----PKPESPVGTAAAPASAPRWRAAKILHCSAGRIRTELVHRARSIGDSLVQTLPLKTPAVQRY 248 
Q6V7I2    441 PRTRLQSA-----SPQKSSVGNSDTPELAPKWRVTKTVCSYAECLRTGLIQRARSFGDVLTQALPCKAPAVQRY 509  Equine arteritis virus
P19811    440 PRTRLQGA-----STQEPLASAGVASDSAPKWRVAKTVYSSAERFRTELVQRARSVGDVLVQALPLKTPAVQRY 508  Equine arteritis virus ...
ADI59062  180 PRTRPPGT-----SAQEPPAKAETASAPVSKWRVAKTVYNSAERCRAELVQRARSVGDVLFQALPLKTPAVQRY 248
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