Conserved Protein Domain Family
CH_SF

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cl00030: CH_SF Superfamily 
calponin homology (CH) domain superfamily
CH domains are actin filament (F-actin) binding motifs, which may be present as a single copy or in tandem repeats (which increase binding affinity). They either function as autonomous actin binding motifs or serve a regulatory function. CH domains are found in cytoskeletal and signal transduction proteins, including actin-binding proteins like spectrin, alpha-actinin, dystrophin, utrophin, and fimbrin, as well as proteins essential for regulation of cell shape (cortexillins), and signaling proteins (Vav).
Links
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Taxonomy: root
PubMed: 615 links
Protein: Related Protein
Related Structure
Statistics
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Accession: cl00030
PSSM Id: 469584
Name: CH_SF
Created: 8-Feb-2008
Updated: 4-Oct-2023
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