Conserved Protein Domain Family
DUF4590
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pfam15257: DUF4590 
Domain of unknown function (DUF4590)
This family of proteins remains to be characterized and is a domain of unknown function. This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: CCE and PCY. In humans, the gene encoding this protein lies in the position, chromosome 1 open reading frame 173.
Links
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Statistics
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PSSM-Id: 464597
Aligned: 12 rows
Threshold Bit Score: 167.553
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ESN95909      191 QLSNSWMVRRDEVVVEQQHCGGSTITVFKDKLCP-GSDFTFVSTRHSDYPFSLTIYVDYKQNTRVSVCCEAKHRKGVRLG 269 
XP_015146568  338 HLSHDDSDYRDEIKVYQQHCGGENLCVYKGKLLE-GETFQFVSKRHRGFPFSLTFFLNGMQVDRLSSCCEYRHQKRSRLG 416 
XP_020953276  300 HLAHDHSDFRDEIKVYQQHCGGENLCVYKGKLLE-KETFQFISKRHHGFPFSLTFFLNGIQVNRLSSCCEYKHRKGSRLG 378 
XP_012402994  380 HLNHDDLNYKDEIKIYQQHCGGENLCVFQGKLLE-KETFQFISKRHFGFPFSLTFFLNGMQLDRLSSCCEFKHRRGSRLG 458 
EGD79465      497 HGVNAQAPVQ---LVVKQQVAASSVVVLRQHILP-NETFSIQSRRKPSQGLGLVFIANGVTLARLSCCCEYKHAPGTYVC 572 
XP_011408160   72 IKLMSVFDPRVYVEVHQQHCGGNNICLFKGKLLA-KDQFTVTSKRHYGMPFGMSLYVNGLINCRISSCCEYKHKQGQVLG 150 
EKC34477      328 TLPRDQYDPTQNISIDQQHCGGNTLTVFKENLKP-GDTFSFISRRHRGFPFSLSIFMDGRVDCRVSTCCEYKHAKGVKLG 406 
XP_008112302  304 HLSYELFDYREEIKIYQQHCGGENLCVFRGKLLE-GETFHFISRRHYGFPFSLTFYLNGIQVDRVSSCCEYKHRKGTRLG 382 
XP_006003352  299 HLFHDDFDYSDEVKIYQQHCGGENLCVYKGRLLE-GENFNFVSRRHRGFPFSLTFFLNGIQVDRVSSCCEFKHKKGSRLG 377 
AAI52052      198 HLSHDDNDFRDEIKVFQQHCGGENLCVFKGRLQE-GETFNLISRRHRGFPFSLTFYINGMQVDRLSSCCEYKHRKGARLG 276 
XP_023195530  287 HLSDHPSILRDEIKVLQQHCGGENLCVYQGKLCE-GDVFQFLSRRHKGFSFSLTFYQNGLLVERLSSCCEYKHSKGSRIG 365 
CAG01451      297 HLAHDLHDTRDEVKVYQQHCGGENLCVYKGL-LHkGERFQFVSRRHRGFPFSLTFFLNGLQVERLSSCCEFKHRRASRLG 375  spotted green...

ESN95909      270 G--NSGMFGIVSVRNPRFCEKCse-------tRKRRKLEKKMKRKNK 307 
XP_015146568  417 G--RHGYFGFLNVEGASPCYRC----------IVAMGLDKKPSPPKR 451 
XP_020953276  379 G--KRGYFGFVCVERSSPCYKC----------IIAMGLDKKTTSPKP 413 
XP_012402994  459 G--KNGYFGFVDIDGASPCYKC----------IISMGLDKKPFPPPK 493 
EGD79465      573 Q--KSSGLRLLHVTGGGPCLRCrvdafianedHKSHVNKQKQERSTV 617 
XP_011408160  151 GgkSSANFRLLKVEGGQPCYLC----------KFGHANQSKLFPPAF 187 
EKC34477      407 G--KMGHFSLLKVEGATPCYKC--------------KLTSKASPRSL 437 
XP_008112302  383 G--KHGHFGFVNVERSAPCYRC----------IISMGLDKKPSPPKR 417 
XP_006003352  378 G--KHGHFGFFDVEGACPCYRC----------IIALGLDKKPIPPKK 412 
AAI52052      277 G--KNGYFGFVNIEGASPCYRC----------IIAMGLDKKPSPPPK 311 
XP_023195530  366 G--RHGLFGFCSMEGASPCYKC----------ILAMSMDRQPIPPPK 400 
CAG01451      376 G--RHRHFGFCSVEGASPCYKC----------IIAIGLDKQPNPPPK 410  spotted green pufferfish
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