Conserved Protein Domain Family
HTH_19

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pfam12844: HTH_19 
Helix-turn-helix domain
Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.
Statistics
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PSSM-Id: 463728
Aligned: 25 rows
Threshold Bit Score: 38.8087
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q2SLS3              18 AQRLKELRSHFGY-TQQKVVDgvnellpLIQHRphplcRSRYAKWELNnRTeMPD-----YPELLALCHYFEQEPYYLLT 91  Hahella c...
EEF24558            53 GRFVRLMRRHKQI-SLEKLAE-------DARVD-----ITELVVIEED-VRhVPD-----ARTVYQLAQQFAVPTSKLMQ 113
Q11MK1              53 GKFVNLMRRRRGF-SMEQLAQ-------AADLD-----ASELLVIEDD-VHyVPE-----PRTVFKLAETFEVSQRRLMQ 113 Chelativo...
Q1QFC5              53 GRFINLMRRQRGF-SMERLAE-------EAELD-----ASELLVIEGD-VHyIPE-----PRTVYRLAQTFNVSQQRLMQ 113 Nitrobact...
jgi:HSM_0248         7 GKIVRKARIDANE-TLLTMSK-------ALGTT-----PAYLSGLETG-SK-KIS-----KKWVVAITHFFKEK--GIEV 64 
WP_012406626        12 GERLLRARKNRGF-TQKQVEM-------HVGIA-----QSNLAELELK----GTG-----SSFTVSLALLYGVNPVWLAL 69  Paraburkh...
wucgs:EUBELI_20065 138 GSMLKCVRDINGItDQLMISE-------DLGIS-----RYKYSKIENN-KE-YPD-----AMVLIRLYELYGYLPTMYLD 198
jgi:Cpin_0919       87 GGRLMELIGERGL-NKTRLAK-------RLGMSr----RTMYNLFEKE----VFG-----AEELDRVVRALEMTTTSFLH 145
jgi:Pden_3746       36 TYALRALREGAKV-GVREMAR-------RLGIS-----PNSYTHYENPnRFkDPYlpmhwAERFADALEPDGVPRDAVLA 102
jgi:Ajs_0932        89 GDRLRQARELCNL-SQSVAAQ-------RLGYSn----SSKLSKVEGAtDTnSVP-----LWLILRAAKVYEVSIDFLFG 151
Q2SLS3              92 GVNG 95  Hahella chejuensis KCTC 2396
EEF24558           114 LAGL 117
Q11MK1             114 LAGL 117 Chelativorans sp. BNC1
Q1QFC5             114 LAGL 117 Nitrobacter hamburgensis X14
jgi:HSM_0248        65 KELQ 68 
WP_012406626        70 GKGP 73  Paraburkholderia phymatum
wucgs:EUBELI_20065 199 LYDV 202
jgi:Cpin_0919      146 PGAL 149
jgi:Pden_3746      103 LAGV 106
jgi:Ajs_0932       152 VTDD 155
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