Conserved Protein Domain Family
MAP17
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pfam15807: MAP17 
Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
MAP17 is a family of proteins found in eukaryotes. It is a small non-glycosylated two-pass membrane protein, that is overexpressed in many tumours of different origins, including carcinomas.
Links
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Statistics
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PSSM-Id: 464886
Aligned: 14 rows
Threshold Bit Score: 103.681
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_854872      3 MGTLEA--LLLLSALLLSPAEAQQATQYHLKPWLVGLAAVVGFLFIVFVLMLANRVWCSKVRAQDEEDTGFRMCSNPYQD 80 
XP_023368258  28 METLETflVLLLGVLFLPAVEAQQATERRLKPWLVGLAAVVGFLFIVFVLMLANRIWCSKARAEDEEETAFRMETNVYHD 107
XP_004771431   3 METLEI--PLLLSALLLSPAKAQQASQYRPKPWLVGLAAVVGFLFIVFVLMLVNRIWCSKKRAEDEE-FAFGMESNPYQD 79 
XP_004865853   1 MSALGM--LLVLATLLLPSVQAQQATERHLKPWLVGLTAVVVFLFIVFVLLLANRIWCSKARAEDEE-TTMRIQPNPYES 77 
XP_002761639   7 MEILGS--LLVLEFLLLSPAEAQQTTERHLKPWLVGLAAVVGFLFIVYVVLLANRVWCSKARAEEEE-AMFRMEPNLYQD 83 
O75264         1 METLGA--LLVLEFLLLSPVEAQQATEHRLKPWLVGLAAVVGFLFIVYLVLLANRLWCSKARAEDEEETTFRMESNLYQD 78  human
XP_008114558   1 MKSLLI--VILCFLVILEPANCQIATGP-LQPWMRGTIAVSVFLVLACVAFVINRIWCQN---KHDSSERRNMGVNKEEE 74 
XP_010714449   1 MPALRL--LALGLLLALEPASCQEARGK-LQPWSQGVIAVVVFLVLVAICFVVNRFWCKK---QQDNVETVVSIGAKEEA 74 
NP_005755      1 MSALSL--LILGLLTAVPPASCQQGLGN-LQPWMQGLIAVAVFLVLVAIAFAVNHFWCQE---EPEPAHMILTVGNKADG 74 
XP_002726917   1 MDTLGR--LLLLATLFLTPAEAQQASERRLKPWLVGLAAVVGFLFIVFILMLVNRVWCSKDRAEDEE-ATFRMDHIVNQN 77 

XP_854872     81 VGVSEEGKRekiee-ikdtKGRKAEKEGERNLGLELEeQEEPRVEGKVTNTAM 132
XP_023368258 108 VHLSKEDKKek------krKEKKTETEGESNSGLELDeEEQRRDHEKTKNTAM 154
XP_004771431  80 TALSDEGKRerkgv-tkdqKDKTAGKEGETNSGLELE-EEESGGHGKVANTAM 130
XP_004865853  78 MGPRKDSKKe--------kKQKKKEKGGESNLGLELE-EKEPEEYEEIK-TSM 120
XP_002761639  84 LSEDKREKKhaqgkeeerkEEKKAAKEGESNLGLELE-EKEPQDHERAKNTAM 135
O75264        79 QSEDKREKKeakekeekrkKEKKTAKEGESNLGLDLE-EKEPGDHERAKSTVM 130 human
XP_008114558  75 VISNGTEGRy-----------SATASNFRCEEGPHVY-ENEVELECESTTAHH 115
XP_010714449  75 VVPNGREGTy-----------VTSAVDFRSKENKHAY-ENTLDPEEKVITTAM 115
NP_005755     75 VLV-GTDGRy-----------SSMAASFRSSEHENAY-ENVPEEEGKVRSTPM 114
XP_002726917  78 SKPSKADKK----------KQKVGRKGGQSNEGLDL--EEEFSDDERDKKTAL 118
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