Conserved Protein Domain Family
LURAP
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pfam14854: LURAP 
Leucine rich adaptor protein
This family of proteins activate the canonical NF-kappa-B pathway, promote proinflammatory cytokine production and promote the antigen presenting and priming functions of dendritic cells.
Links
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Statistics
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PSSM-Id: 434270
Aligned: 6 rows
Threshold Bit Score: 155.31
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
D4A8G3        39 TSGDVLLPGASSTGHGLGDKIMALRMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLtGGS 118 Norway rat
XP_003450373  42 HSGNCKCCANSADLKRLESKMLFLKQEMANLRAIDVKLMQQLMSINEGIESIRWMIDDKGSVTSHDDSLTGSLYSLsDSQ 121
Q4SAP6        44 TSSSCKRRSKSADVERLEDKLLFLRQEMALLRAIDVKLMQQLMSINEGIESIRWMMEDKGGVASPGGSLAGSLYSLtDSQ 123 spotted green p...
Q5BJW5        70 PASGSPRRSHPSALERLETKLHILRQEMVNLRATDVRLMRQLLLINESIESIKWMIEEKATVTSRGSSLSGSLCSL-LES 148 Norway rat
NP_001099178  39 MVSHHQTDNNETEKKGLDGKIRKLKMEMAHLRAADVKILNQLLALHEGIEAVKWLLEERGALTSRCSSLTSSQYSL-GEG 117
XP_015211171  44 KLSTSESMDRESGKKGLAEKIRDLKLEMAYLRSIDVKILQQLVAVHEGIEAVKWILEDKSNLTSRCSSLTSSQYSL-VES 122

D4A8G3       119 PERSRRGSWDSLPDTSstDRLDSVSIGSFLDTVApRELDEQ 159 Norway rat
XP_003450373 122 DGASLRGSFNSLNDGNs-DGLDGLSVGSYLDTLA-EDLPDD 160
Q4SAP6       124 EGSSTRGSLNSLNDCS--DDLDGLSVGSYLDTLA-EDLLGD 161 spotted green pufferfish
Q5BJW5       149 QSTSLRGSYNSLHDGS--DGLDGISVGSYLDTLA-DDVPGH 186 Norway rat
NP_001099178 118 PDTSWRGSWSSLQDPH--DELDNISIGSYLDTLA-DELDEY 155
XP_015211171 123 QDTSWRGSWNSLQDPN--DKLDNISIGSYLDTLA-DEMDEY 160
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