Conserved Protein Domain Family
DUF3754

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pfam12576: DUF3754 
Protein of unknown function (DUF3754)
This domain family is found in bacteria, archaea and eukaryotes, and is typically between 135 and 166 amino acids in length. There is a single completely conserved residue P that may be functionally important.
Statistics
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PSSM-Id: 403691
Aligned: 25 rows
Threshold Bit Score: 99.2571
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_009543141  162 ERVVLLIKFKG---------------------------------SGYFQAKAKKNKKYqdl-nfTPGKMYLYFYKNIPKL 207 Crocosphaera s...
XP_004995464  290 KEMVVLYR------------------------------------TAEQRDEAAQRPG-------IPPSISVKSFKNIPVA 326
CBJ25706      451 EVVVVYFKRTRrpifktpatlatllragtkignkvrgvekvdaaQDDADEVKA-----------AGLGLQLRVYRGVPLV 519
NP_850462     475 EELILLYT------------------------------------KDASEKDDKNKDE-------TRSSLQLEIFERIPIP 511
XP_010661543  427 EELILLYT------------------------------------EEVSEGESKYKSEVp--------SLQLKIYERIPIP 462
XP_018675501  345 QELVLLYN----------------------------------------EKEDQNENDIp-----GIDPLQLKIYEKIPIP 379
XP_002296116  545 EEVVVVWRPMRnkkrhtiqsnwvdpvk--rwlynaakifdmeeqWPSLKPDEQIKTYIeadvgdGPLPLEIKAFYDVPMA 622
XP_002184998  501 KEVFVVWRPLSdrrpkmpairppkf------aydladmfdieglLPKKETAPAE----------APHRVEIRAFSDVPMA 564
WP_012913499  195 QRLVVMFQL-----------------------------------KDGTEHAAEVPGAIg-----RRDAVVLKLFKNIPKM 234 Pirellula staleyi
jgi:Rvan_2185 179 tswktawlierpvevdayrrlfiglklkpvetrvaeimriekisREKAEKRVKKIRNQkmlegvSEETLHLKIFRRIPKS 258
WP_009543141  208 DLDLLFPNIKTSMTWKDKLLFGVPAIGAAVPLVVRAIpnilliivaillllkadsvvdsievDQRKVRDIMPILVATLSL 287 Crocosphaera s...
XP_004995464  327 DFEIVLPCQRPTTRALDLVKVLAAVLVALATVATKFWqfyeee-------------keendwHTSTWQERFSEIAPLLII 393
CBJ25706      520 NLNSIAPDKKVEVRPQTALRLDLNTVVGLGLVLANL--------------------------RFDSP-------VLVAAA 566
NP_850462     512 DLPVIFPHKKLYFRIIDTVRLDIASILGLTAYFVNY--------------------------KFENISSSPSAFFLDVIA 565
XP_010661543  463 DLPVVFPHKKLSFRIIDTVRLDVATILGLLAFFINY--------------------------KFEDILSSPSAILLDVIA 516
XP_018675501  380 DLPVIFPHKKLSFRILDTVRLDVASLLGLLAYFINY--------------------------KFENIASSPSAVLLDVIA 433
XP_002296116  623 NILAVLPKTKLVFRQADAFVFDLVSVVSFLAVVGSV--------------------------KFDSPR-------LDLIA 669
XP_002184998  565 NLPAVLPSTKLVFRPADAFVFDFISFFSFFVVFGSL--------------------------KFDNPK-------LDLLA 611
WP_012913499  235 DVDMLLPGTQIRMTWLDQGKIWLPTISGVGIVALKLLq-----------------------gAAGIAMAGLQGTIATISL 291 Pirellula staleyi
jgi:Rvan_2185 259 DIEILFPNAKIKFNLFDKLWLWIGSGGSTIFAIVMA--------------------------ALKFVAAVALSLFFVIFT 312
WP_009543141  288 TMTLGGFAVKQYTKYKSKEIKFQKEVSDTLFFKNLANNSS 327 Crocosphaera subtropica
XP_004995464  394 VG---TYASKILVQIRTQQATYQNLMTNYLYQRTTDSDDG 430
CBJ25706      567 TVSVVLLVIRTIVGYLNARIRVESFVSRDILDKTMGSNvp 606
NP_850462     566 VTALVIYATRVVLGYKQTWDRYQLLVNKTLYEKTLASGFG 605
XP_010661543  517 VSALIIYVTRVALGYKQTWDRYQLLVNRTLYEKTLASGFG 556
XP_018675501  434 ISALIIYLSRVVLGYKQTWDRYQLLVNRTLYEKTLASGFG 473
XP_002296116  670 FVALGSLAVRTFFRYSNKYARYDLLVNKFLTQKISHRGPG 709
XP_002184998  612 VLSVSLWLFRTFIRYSNKLARYDLLVKKFLTSKITHRNSG 651
WP_012913499  292 VGGTIGYGIRSFYGYLQTKDRYQLSLTRSLYYQNLDNNAG 331 Pirellula staleyi
jgi:Rvan_2185 313 IAGAVGAIIRSFTSFLNTRTRYMAKLAQSLYFHNIASNQs 352
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