Conserved Protein Domain Family
bHLH_AtILR3_like

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cd11446: bHLH_AtILR3_like 
basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana protein IAA-leucine resistant 3 (ILR3) and similar proteins
ILR3, also termed AtbHLH105, or EN 133, is a bHLH transcription factor that plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. It may regulate gene expression in response to metal homeostasis changes.
Statistics
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PSSM-Id: 381452
Aligned: 16 rows
Threshold Bit Score: 99.7149
Created: 14-Jun-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative DNAputative dimer
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:The N-terminal basic region of bHLH mediates high-affinity DNA-binding to specific hexanucleotide sequences
  • Comment:Based on the structure evidence that Arabidopsis thaliana MYC2 (5GNJ) binds DNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1      ##  ## ##   #                   ##                                           
Q9FH37      76 KACREKQRRDRLNDKFMELGAILEPGnp-pKTDKAAILVDAVRMVTQLRGEAQKLKDSNSSLQDKIKELKTEKNELR 151  thale cress
CEG02114   104 KSTREKKRRDALNSRFEELQAVLEPGaa-tKADKATVVAAATVFIKRLRAEHARLAEGIMRLQEDNIQKAKLTKALA 179  Ostreococcus tauri
Q9LTC7     167 KACREKLRREKLNDKFMDLSSVLEPGrt-pKTDKSAILDDAIRVVNQLRGEAHELQETNQKLLEEIKSLKADKNELR 242  thale cress
Q9LT23      63 KAGREKLRREKLNEHFVELGNVLDPEr--pKNDKATILTDTVQLLKELTSEVNKLKSEYTALTDESRELTQEKNDLR 137  thale cress
EFJ35991    75 KACREKMRRDRLNDRFVELSAALEPGrp-pKSDKATILSDAVRVITQLRAEAQQLKESNEQLRDGIKELKAEKNELR 150  Selaginella moellen...
Q8W2F2      49 KAEREKLRRDKLKEQFLELGNALDPNr--pKSDKASVLTDTIQMLKDVMNQVDRLKAEYETLSQESRELIQEKSELR 123  thale cress
Q8L467     135 KACRERLRREKLNERFMDLSSVLEPGrt-pKTDKPAILDDAIRILNQLRDEALKLEETNQKLLEEIKSLKAEKNELR 210  thale cress
PNR45654   114 KADREKLRRDRLNEQFGELAGVLDPDr--pKNDKATILGDSVQVVNELRSEVKRLKCEQTALLDESRDLQQEKSELR 188  Physcomitrella patens
PNW83495   120 KACREKARREKLNERFLELSRLVDPGse-pKTDKSTILGDAIRYVQQVTVENHQLKQLNKFLEERVCTLERERGQQL 195  Chlamydomonas reinh...
PSC71812  1030 KACREKARREKLNECFDELARLCDPTgkmsRTDRISVVQDAIRAMGALRVEVNQLRQLNKFLEERVRHHESARAQNM 1106 Micractinium conduc...

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