Conserved Protein Domain Family
EMP70

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pfam02990: EMP70 
Endomembrane protein 70
Statistics
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PSSM-Id: 460774
Aligned: 301 rows
Threshold Bit Score: 159.248
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EPE08851             57 QYA-YYDLPfVCPPT------GQhrigsllsGQnIplNIG-EVLR-GDRISASDIKLNMGHNAECSYLCTREISRKELNW 127
WGS:AATM:SJAG_01445  43 TYT-YYDLPfVCPFGstk--------------asHrsSLG-DVLM-DNRFSSTNFQIRMLQDVSCKNLCELKLSDEGKGS 105
CCF60549             63 PYG-YYDLPfICPPT------NQr-------KP-LhmSLT-EILR-GDRKWQSDYSLTFGKDNDCAVLCARKTTPEGIQK 125
Q6FTC9               77 PYA-YYDLPfICPPT------KEk-------KP-LhlSLD-EIFR-GDRKWQSDYKLSFGIDSPCEILCARKTKKEGMIK 139 [Candida...
CCC68010             68 PYA-YYDLPfTCPPT------MHk-------KP-LhlSLN-EIIR-GDRKWQSDYILNFGEDDQCHILCTRKTTKEGMKE 130
CCD22309             67 PYA-YYDLPfTCPPT------MHk-------KP-LhlSLN-EIIR-GDRKWQSDYILKFGQDDTCHILCTRKTTKEGLKN 129
CCE91160             67 PYG-YYDLPfTCPPT------EDk-------KP-LhlSLN-EIIR-GDRKWESDYKLKFGQDASCEALCARKTKPAGMRR 129
CAR26187             67 PFG-YYDLPfTCPPT------PEk-------KP-LhlSLN-EIIK-GDRKWESDYKLVVGQDNPCEILCARKTTREGLQT 129
CCH62697             88 PALcYYDLPfVCPPSdtkrpiH----------N----SLT-ELFN-GDYLSESDYILEFAKDEPCHILCSRKTSKKGMQR 151
EDO18042             75 PYI-YHDLPfVCPPTsvr----------------kpvHLEfDSLFrGDTLSESDYKLKFGDDYECEILCARKTNKNGVSK 137
EPE08851            128 AKEMVRDGYVVEWIVDN-LPGATSFVTvdksh----kyyaaGFKLGFTDssSGrpRYFLNNHHTIVIRYRKaaGRAgdrg 202
WGS:AATM:SJAG_01445 106 AKEYIENEYKINWSLDD-LPAAlkpavtg-----kdvryvsGIPFGNISy----gKVFLYNHFDFIIRYRPasLIQs--d 173
CCF60549            126 AINLVKKDYIVQWSIDNdLPASTTFIStsenr----kyyipGFSLGFVD--PDteTAYLNNHVMLVIRYHAi-DDE---- 194
Q6FTC9              140 AKELVQQGYVTQWLIDEsLPAATTFISstnhn----kyyaaGFPVGYVD--DRtgKTFLNNHVMLVIRYHPv-SEE---- 208 [Candida...
CCC68010            131 AQELVKNGYVVQWLIDDeLPAVTTFISttdhk----kyyasGFPLGFVD--PEtgKTYLNTHVMIVIRYNTv-DTN---- 199
CCD22309            130 AKKLVEDGYVVQWLIDEeLPAATTFIStidqk----kyyasGFPLGFVD--PDtgKVYLNTHVMLVIRYNTv-DVN---- 198
CCE91160            130 AQELVRQGYVVQWLIDQeLPAATTFIStidhk----kyyvsGFPLGFVD--PDteKTYLNTHVMMVIRYNAi-DPE---- 198
CAR26187            130 AKDLIKSGYMVQWMIDDdLPAATTYISttdnl----kyyapGFPLGSVD--PRssRVFFNNHVMLVIRYNLv-DSD---- 198
CCH62697            152 AYDLIKNDYIVQWYVDNdLPVG----TtyisnkvnkkqylpGFSLGYFDn--QtgQAYLNTHLMFVVRYHAvtS-D---- 220
EDO18042            138 AIDMIKQDYQILWSIDDeLPIS----MpyistitqrkkyipGFPLGRFDk--DknKVYLYNHSMLVIRYNAidD-D---- 206
EPE08851            203 ENVIVAFEVFSKSIGSSnrrlesgCPadlLHidq-nfeLylapNHtaaqedpdryahlsyhpdsaeeanDdndG-GVLSI 280
WGS:AATM:SJAG_01445 174 KWQIVGFEVLPISQADAt------CP------------------Dayltdnk-----------dvsgneYv-lDsQVSDV 217
CCF60549            195 HFTIVGLEVYPKSVSDYh------CPgasRNyeq--feLva-nDD----------------------------E-EVTYI 236
Q6FTC9              209 EFTIVGFEVYPKSVSDYh------CPganKNhdk--yeIivpeKD----------------------------D-ELTFI 251 [Candida...
CCC68010            200 KHTIFGFELYPKSTVDFh------CPgasKDyeq--yeLvvpeND----------------------------D-DLTFI 242
CCD22309            199 KHTIVGFEVYPKSVSDFh------CPgasKNyep--yeIvipeND----------------------------D-DLTFI 241
CCE91160            199 TFTIVGFEVYPKSVSDYh------CPgasKGyeq--yeLivpeNE----------------------------D-ELTYI 241
CAR26187            199 KVTIVGFEAYPKSVSDYh------CPgasKDfkp--feItdppL-----------------------------E-EIVYI 240
CCH62697            221 TFTIVGLEVYPRSIVDYn------CPgasKDfiplevkVpennD-------------------------------DPTYL 263
EDO18042            207 KFTIVGFEVYLRSVSDYh------CPgasKNyeeyelvIpendD-------------------------------DLTFI 249
EPE08851            281 PYTYSVYYQEDNtVEWGHRWDLYFv----NQeegSKI--HWLAIINSLIIC-----------GLLTGIVLMIFAKTI-RT 342
WGS:AATM:SJAG_01445 218 QYSYSVRFVLDEqTTWGQRMKKYVtytslYD--------RKYGFMNAIIII-----------FLLSTFVTGIVSQQLfTK 278
CCF60549            237 PFTYSVYWREEFdVEWKDRYSFFSnsgelSKeitDKF--RWILLANSSGLA-----------LFISMIVSVIFLRIS-KK 302
Q6FTC9              252 PFTYSVYWREEFeVDWNHRWNYFLnngelSNskaNQF--HWMSFLNSVGIA-----------SMTTTIVSIILLKIF-SK 317 [Candida...
CCC68010            243 PFTYSVYWREEYlVDWEHRWDLYLnagelSNdksKQF--HWISLANSFGIV-----------FLISSITAVILYRTF-KI 308
CCD22309            242 PFTYSVYWREEYlVDWDHRWDLYLnsgelSEnktTQF--HWISLANSAGIV-----------FLMSFVVSVILLRSF-KS 307
CCE91160            242 PFTYSVYWREEFkVDWSHRWNFFLnsgemSEassRRF--HWMTLGNSVGIS-----------FLLMLIVIANLYRIV-RV 307
CAR26187            241 PVTYSVYWREDAeIDWSDRWSLYInraqlADsssSTF--HWMALANSVGIV-----------LFVTFIVIVNLIMIF-R- 305
CCH62697            264 PFSYSVYWREEFdLPWNQRWDLFKtade--llreKDLsfHWYSLINSNSITvg-------viTFLCLVISMNRMRIL--- 331
EDO18042            250 PFTYSVYWREEFdIDWTSRWNLFD----------NDIeeEDPKLINKSMLSnimqptrtglfLLPLIIFSIIIVKVVeNG 319
EPE08851            343 DIKAYKDSEEgrrlkrrsrragraradgttaneklpassvgvgsgglpdqdggglesvslendiltsedealEDV---TG 419
WGS:AATM:SJAG_01445 279 KYENYeqlq------------------------------------------------------------eeglESedsDT 298
CCF60549            303 NKNENS--A---------------------------------------------------------------IES---KK 314
Q6FTC9              318 KERESRNINTstnl-------------------------------------------------------gqdNED---DN 339 [Candida...
CCC68010            309 SR---RSFSDis-----------------------------------------------------------kEED---DK 323
CCD22309            308 SR---DISTDin----------------------------------------------------------ksEEH---RN 323
CCE91160            308 GHEAGSEEFQftf--------------------------------------------------------denEEA---DS 328
CAR26187            306 -----NPNEQle----------------------------------------------------------skENE---DS 319
CCH62697            332 -YN---------------------------------------------------------------------------KS 335
EDO18042            320 EKNKFtt-----------------------------------------------------------------eAQlasKC 334
EPE08851            420 WK----LL-HGEVFRTPRF-----------SYIL-APLVGSGMQLLFMAFGLVFLSAIGVLN---PSFRGGFISFGIGLF 479
WGS:AATM:SJAG_01445 299 WK----LV-KTDVFRPPAH-----------PRLF-SALFGAGCQFAAMCMFLVLLGFLGW-----AQKKASVVNSAIALY 356
CCF60549            315 ----------GSMDVIARKwlrnd--rtihFNFL-IVLVSFGVHFAFTLLGSLAISCSLQKF---DNIRNSVLTLVLLFF 378
Q6FTC9              340 DD----KI-SGSVFVNAKTwitvg--kipyWKAL-ICLTSMGIQFSFTILGSLIISCSLSKL---HNIRFTVLTMSLICF 408 [Candida...
CCC68010            324 ----------GSIYVVARKwllne--qtplANVL-IIFVSMGVQFLFTVLGSLIISCSLKKL---HNVRDSVLTMGLLCF 387
CCD22309            324 ----------GLVYEVARNwiine--rtplANLL-ILFVSMGVQFLFTVLGSLTISCSLNKL---HDIGDSVLTMAVLCF 387
CCE91160            329 ------------IYGVAKTwlaqtdsssisFKIL-TIFVSIGVQFLFTIIGSLAFSCSLNKL---HNIRNSVLSVASFFL 392
CAR26187            320 ----------SDIFNVANNwlrar--qgfqLNRL-IVCVSMGIQVMFMILGPLAISLSLTRL---HNIKNSVLTIAALCF 383
CCH62697            336 WKkrqlSItTTTTTRYPNI--------------F-TICITSGIQFFFLLISSVLIT----FQiskFHQIKDTIIVALFFI 396
EDO18042            335 W------IeSNNINLKSSF-----------SASIlTLVISMGVQSIFSLIGIIILK----LSiykLHDISNIVLLNIFIW 393
EPE08851            480 VFAGLFSG-YFSARV--------------YRTFG----GQ-NWRRN---------TTVTAILFPGLLFSAVFVLNLFVWA 530
WGS:AATM:SJAG_01445 357 VLTGVFAG-YFSQSL--------------YHSFG----TDkEWKKV---------GVLTASLVPFLVSFFGMVINFFFFV 408
CCF60549            379 VLGGFMAS-FVGTCLimqknktmykgslkRlhys------------------plfAMCCGSLLPAVIMIITIFLNNIVWA 439
Q6FTC9              409 ICGAAISG-YIGSRLyiey-------qilKGYLR----NE-VNRTKvy-----kfSVVCGSSLPGLLMVISFSLNCIILA 470 [Candida...
CCC68010            388 VTGAFMAS-FTGAHLlksreemcsesqmkPtryy------------------pvfALLCGSLLPSFVMLVALLLNSIVWA 448
CCD22309            388 VLGAFMSS-YIGSVLlrlknkatmkkqpiKkgfh------------------lffAILCGSFLPGIVMIVTLLLNSIVWA 448
CCE91160            393 CHWSYLWHlFVGTWLhidhrtt-ndgsagRcr---------------------tfSILCGSALPGLVMISTQMLNWIVWA 450
CAR26187            384 VAGAFMAS-FVGTWLkmd------------------------qnISaytfynpvfAVLCGSALPGSIMVLTLSLNCIIWI 438
CCH62697            397 AFGIIVSV-FIGTLI--------------QRTFiltnfpDkYYLTN---------PILFGSTLPAFILLSMFIINSIIYL 452
EDO18042            394 FIEGILASsFLGTWL------------------------RmNILNKksinynpkfSILCGSLLPFLLMIFVYPIHSIVWL 449
EPE08851            531 QASSTAIPFGTVIGILLLWLCIQMPLVYAGSWYGFV--------------------------RA-GPwEHPAKT-STIPR 582
WGS:AATM:SJAG_01445 409 SSSSRVIPFSTILGLLALWVLINAPLVFVGSAIALR--------------------------W--PIfEQTIVN-SQVSR 459
CCF60549            440 HGSSRALPLKTILFLISIYFIVCIPLSLLGGSYASDicqkrtlr-----------afsspaqQKlAVtNSN--------- 499
Q6FTC9              471 HDSTNALPFKTEVFLVSIYFVTCIPLSLLGGVLALNckvds-----------------yntlKRiTSlRRN--------T 525 [Candida...
CCC68010            449 HDSTHALPFGTVLFLISVYFVVCIPLSLLGGYIAVKstn---------------------skPSfS---FS--------I 496
CCD22309            449 HDSTHALPFKTVVMFITVYFIVCIPLSILGGYMA-Nssk---------------------tkGSlTDpKFH--------T 498
CCE91160            451 NESSHALPFRTIVLFVSIYFVICIPLSLLGEEVSHRvhrkqaqnf---------pilsslgaRSiKPcRAP--------- 512
CAR26187            439 WDSTKALPFGTMVVFVSWYFVVCIVVSLLGGAVAAQmhrsvrhd----------appattasD----------------- 491
CCH62697            453 SEKNHAFPFKLSMYFFTSYFILSIPLSIISGVLSTR---------------------------FiSFpKYPSRSlPTSPN 505
EDO18042            450 IESSSRYPFKTLTMMISFFYIICVPFSIIGGGLAKKyrkhykemfgnitldnenndndekkrFKaQHrPSSINK-NKLG- 527
EPE08851            583 ---QIP-V---QA-WYIR-DI------------------RSVLLAGLIPFAVIFIELLFVFQSLWQDKsgYY-YVFG--- 631
WGS:AATM:SJAG_01445 460 ---SIP-R---QP-WYLKfPY-------------------NVLFSGCLPFCSIFVEVCNLLAITWKENnaFF-FFFD--- 508
CCF60549            500 --------------------Lartiksi----fddpfsgLLASIGGLFPFFIIYVELQHVYKFVWLEKasFY-YLRW--- 551
Q6FTC9              526 ---ISR-Ks--RS-DFTK-KVslyqrlvfd-ikhdsfttFGALAGGFFSFIIIWVELQYVYKSVWLEKtsFY-YYYG--- 592 [Candida...
CCC68010            497 ---GNY-Sd--RI-FVYK-TItmspsvl----inrplssLAILAGGLFPFIIIYVELQYVYKSLWLEKttFY-YFYG--- 560
CCD22309            499 ---SRP-El--EL-FANK-LKpkkhiflfgarlksikiaLPILLSGIFPFVIIYVELQYVYKSVWLEKtaFY-YFYG--- 566
CCE91160            513 --------------TTLA-PRkiser--------ltfdfATFAICGFLPFAVIYVELQYIYKSVWLEKtdFY-YLYG--- 565
CAR26187            492 -----------RK-VLRR-SRaisgk---------lvvfLAGLISGFLPFVIIYVELEYLYKSVWLEKttLY-YLYS--- 545
CCH62697            506 lnlDFEkTsstSSsSSLS-KYsmkyr--------vamilLYLSLTGLIPSIILYLEISLIINSVWNLNsnIYqLLIV--- 573
EDO18042            528 -------------------TL------------------VYSLITAIVPFFIIKSELYWIFTNKWLN----YtTFIKsfi 566
EPE08851            632 FLAVVSTILVVTIAEVTVVTVYIQL-----------------CSE----NHN------WWWRSFIV-GgSSSIWVFLYCI 683
WGS:AATM:SJAG_01445 509 YLFGMIVVITLTISLTAIISVYTLL-----------------QSE----NYH------WWWHSLLIgA-SPAIYLLLYAI 560
CCF60549            552 FLFANIIILCIVVVEIAIISAYIMM-----------------HSS----RSSle--nsWRWRSFQI-SsSCAWYMELYSL 607
Q6FTC9              593 FLLANILILSIVTIEIAIIGCYVML-----------------K-A----KNDrylrhtWGWKSFLM-GsSCAWYMELYSL 649 [Candida...
CCC68010            561 FLLANILLLCIVICEISIIGTFILL-----------------NSA----DKNsn---nWRWTSFQI-GaSCAFYMEVYSL 615
CCD22309            567 FLFANILLLCIVVGEIAIIGTYTML-----------------HMA----DRNnt---dWRWISFFM-GsSCAWYMELYSL 621
CCE91160            566 FLLANIILLCIVVCEVSFLGCYVMM-----------------RKH----KRVatf-dsWRWKCFMM-GtSCAWYMELYSL 622
CAR26187            546 FLFANVLLLCIVVCEISLLGCLVLM-----------------KLN----HKFind-qnWRWRCFVI-StGCSWYMEIYSL 602
CCH62697            574 ILISSQILCIIITSISYLINSQFIFrntntnttttnpltnnnNANnsnnNNNnnnkisWQWRSFFIgA-SPFIFIEFYIF 652
EDO18042            567 FLIIKLFIIIITVSSTSLVGLFVNI-----------------MMTkkgiSQWrddpisLRWSCFLNsF-NICYLTGLYSL 628
EPE08851            684 WYYFA-KLHI-TGF 695
WGS:AATM:SJAG_01445 561 YFYFQ-NLRT-YSW 572
CCF60549            608 YYIFY-VLNT-TGF 619
Q6FTC9              650 YYIFF-VLNM-QGF 661 [Candida] glabrata
CCC68010            616 YYVFF-ILNI-RGF 627
CCD22309            622 YYVFF-ILNI-RGF 633
CCE91160            623 YYIFH-TLKM-TGF 634
CAR26187            603 YYIFF-IIHM-TGD 614
CCH62697            653 YFVFGiKVITvSAT 666
EDO18042            629 YYIIE-VIRI-HGF 640
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