2H6L,2P6Y,3HTN


Conserved Protein Domain Family
PCC
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pfam03479: PCC 
Plants and Prokaryotes Conserved (PCC) domain
This is a Plants and Prokaryotes Conserved (PPC) domain found in proteins that contain AT-hook motifs pfam02178 which strongly suggests a DNA-binding function for the proteins as a whole. Proteins with PPC domains are found in Bacteria, Archaea and the plant kingdom.The PPC domain has a single alpha-helix packed against an antiparallel beta-sheet, which is formed by five beta-strands. There are three highly conserved histidine residues, eg at 117, 119 and 133 in Swiss:Q46QL5 which appear to form a zinc-binding site, and the domain has been observed to form homotrimers. The domain co-occurs with a thioredoxin-like domain in uncharacterized cyanobacterial proteins.
Links
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Statistics
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PSSM-Id: 460940
Aligned: 341 rows
Threshold Bit Score: 54.0639
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2H6L_A         11 GFLLRLDYGKDLVRQIEEFLEEKgIHAAHISAIGAVRSAVigyydqekkeyvkkelxE-PLEILSLSGNVSXKdSkpf-- 87  Archaeoglobus ...
WP_012797702    9 RILIRVDKDEEIVQTILDVCRKEaVRGGVfVGIGGCDWANvgsyvpekgtfkdhevaG-VLEMVSLNGN-VTe-Edgela 85  Slackia heliot...
WP_014243773    9 lVFVVIDKGEDLFSSLYKVQSELgFLGAQVSGIGALKDIEigffhcde-knydrttiEsEKELLALNGNFTFnegk--pf 85  Halobacteriovo...
CCZ44620       10 rYFLSIDNHCEVAAALTEFCRKEnILAGEIYGLGAVNDVVlrflnpatkkyvdmefkE-QMEMANLTGNISEKdGnvy-- 86 
CDA92773       26 QYIVSISNGEELMNALTAFCQERnVTLGTITGIGAIDEMTlrffnpttkqyedrkfeE-QMEIANLTGNVSTLnGkiy-- 102
3HTN_A         17 KYIVSINNHTEIVKALNAFCKEKgILSGSINGIGAIGELTlrffnpktkayddktfrE-QXEISNLTGNISSXnEqvy-- 93  Bacteroides th...
EGJ70650       10 RFIVSLKNGTEIVKALQHFCKEMnIRSGIIAGIGSIDEIRlrffnaktkqyssqqfqE-QMEIANLMGNISTYnKdiy-- 86 
Q2G0A3          9 TILLVLEKGEDIVECITTFADDQdLTFTSVSGIGACDDVVlkffnlttkqyeekhitE-PLELTSLLGNISRLdNghf-- 85  Staphylococcus...
CBL37260       51 QYVIRIDKGEEICAKLKEVAQKEnIKLAYLTGIGAAGKVTagvfdtkekvfkghtweG-DLEIVSIGGNINTMnGety-- 127
jgi:Cphy_0700   9 HYVIRLDRGEDIVAKLKELATTEqIKLATLSGLGACGKVTaglfdtsqkvyksytfeG-DLEVVSLGGTITTMnGdiy-- 85 

2H6L_A         88 chIHVLLGKd----GEVYGGHLFsA-EV--FACEVFVLPLSG 122 Archaeoglobus fulgidus
WP_012797702   86 vhAHVAFSSfegdaCTTVAGHLLsA-HVc-FTAEILLTVtgp 125 Slackia heliotrinireducens
WP_014243773   86 yhLHTVLGNe---dYTTSGGHL--FsATvaVTCEVYLQVhni 122 Halobacteriovorax marinus
CCZ44620       87 lhLHATFGRs---dCSAICGHLFsA-VIs-GACELVVIPSKA 123
CDA92773      103 lhVHVTLGRa---dFTALAGHLLsA-RIh-GAGEFIVEDLQD 139
3HTN_A         94 lhLHITVGRs---dYSALAGHLLsA-IQn-GAGEFVVEDYSE 130 Bacteroides thetaiotaomicron VPI-5482
EGJ70650       87 lhIHITLGRs---dYSAIAGHLLsA-TIs-GTGEFLVEDFDa 123
Q2G0A3         86 ahLHATFGTq---sYETFSGHLAkA-IVs-ATAEIILTVTDl 122 Staphylococcus aureus subsp. aureus NCTC 8325
CBL37260      128 thFHISVADe---aGNVYGGHLTeA-VIs-GTGELVLTEIEG 164
jgi:Cphy_0700  86 thLHISVSDe---nGNVYGGHLNeA-IIs-GTGELVLTVIDG 122
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