Conserved Protein Domain Family
FAF

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pfam11250: FAF 
Fantastic Four meristem regulator
FAF is a family of plant proteins that regulate the size of the shoot meristem by modulating the CLV3-WUS feedback loop. The proteins are expressed in the centre of the shoot meristem, overlapping with the site of WUS - the homeodomain transcription factor WUSCHEL- expression. FAF proteins are capable of modulating shoot growth by repressing WUS in the organizing centre of the shoot meristem. The ability of plants to form new organs throughout their life cycle requires tight control of the meristems to avoid unregulated growth. Plants have evolved an elaborate genetic network that controls meristem size and maintenance. WUS and the CLAVATA (CLV) ligand-receptor system are at the core of the network that regulates the size of the stem cell population in the shoot meristem.
Statistics
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PSSM-Id: 463248
Aligned: 68 rows
Threshold Bit Score: 39.0547
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002972616      34 EFPPPMPSLArtSyNhlplqvPWTLLSANRSNNRVVLHEIKAAHGAQLmlFQPIRSQGRLVLQM 97 
ERN07472         150 NFPPPLSTL---SkNg----qVSYFLKPVKTEGRFILREVVIL-RQEV--LRACRENGRLRLHM 203
KRG96879         132 SFPPPLSSL---NrNg----kPSFYLRPVRKDGRLELTEVRIQ-RSEI--LHASRHNGRLTLRL 185
XP_003535351     133 NFPPPLSSL---NgNg----qPSFILVPVRKNGRLQLTKVRIK-RPKI--LYATRQDGRLRLLL 186
EFH70860          89 KFPPPLSSF---NgRg----kRSFYLRPVRKDGRLELTQVMIN-RPEI--FHASREDGRLRLHF 142
XP_006361886     148 EFPPPLSSL---SqDg----kPNFFMRAVRKDGRLELTEVKID-RPKT--FRASRQDGRLRLHL 201
XP_019071453      55 SFPPPLSSL---NqDg----kPIFSLKPTRKDGKLELNEVKMDIPSSI--VVTSRQQGRLRLNL 109
JCVI:AT3G63020.2 111 DLPPFLTTLDcnGr-------PRFHHRRVRSEGRLEIASVAVDSPE----IVSVR--GREGLRI 161
XP_003576304     186 EFPPAIRSV---GrGg----rPSVCFRASRGEGRFVLTRVVIP-GKEL--LHASRGGGRLRLQF 239
XP_003577033     181 TFPPPIRSIAsgGrGg----kPSVCFRSFRAEGRFVLVEVVIP-GKEL--LHASREGGRLRLQF 237
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