Conserved Protein Domain Family
Pat_SDP1-like
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cd07231: Pat_SDP1-like 
Sugar-Dependent 1 like lipase
Sugar-Dependent 1 (SDP1) lipase has a patatin-like acyl-hydrolase domain that initiates the breakdown of storage oil in germinating Arabidopsis seeds. This acyl-hydrolase domain is homologus to yeast triacylglycerol lipase 3 and human adipose triglyceride lipase. This family includes SDP1 from Arabidopsis thaliana.
Links
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Statistics
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PSSM-Id: 132869
Aligned: 7 rows
Threshold Bit Score: 494.278
Created: 19-Feb-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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active sitenucleophile
Feature 1:active site [active site]
Evidence:
  • Comment:Based on the crystal structure of semet patatin (1OXW)
  • Comment:catalytic dyad is formed by Ser and Asp
  • Comment:oxyanion hole is formed by two Gly and one Arg
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                        
NP_196024    162 MRADLVRNLGNMCNs------eLHKGRLQVPRHIKEYIDEVstqlr----mvcnsDSEELSLEEKLSFMHETRHAFGRTA 231 thale cress
XP_001760387 169 IRADLVRNLGNMCNp------eLHKGRLQTPRLIQEYINEVryhlr----avcgsDSDSFTLDEKIAFIHETRHGFGRTA 238 Physcomitrella ...
XP_001691785   4 LRTDLIRNIANIAKs------qLHEHFVSIPDDIGRYLAEMkeqla----qlvewPEDELSAEEKLAFFRETRHTFGRTA 73  Chlamydomonas r...
CAL57958      84 LRADILRNLGSLMHdskvrfstPSSEPQAVPRVVRQYMAELksql------fsiaQDEKVTIQEKLIFLQETRHCFGRTA 157 Ostreococcus tauri
EAZ29017     159 MRGDLVRNLGNMCNp------eLHKGRLEVPKLIKDYIDEVsaqlk----mvcesDTDDLLLEEKLAFVQETRHAFGRTA 228 Japanese rice
EEC43916      68 LRASIGRNKFGLLHeg-----lFSKALAGTKVLVETYHNVVcaaldfccdapvspDEDPIPTDARLAFFNETRHAYGRTA 142 Phaeodactylum t...
XP_001785954  88 LRADLFRHLGNMCNp------hLHRYRREVPAAIRDYIKEVgnhlq----avyemDVEEFSLEEKLTFMTETRQRLGRTA 157 Physcomitrella ...

Feature 1             ## #                        #                                              
NP_196024    232 LLLSGGASLGaFHVGVVRTLVEhkLLPRIIAGSSVGSIICAVVASRSWPELQSFFenslhslqffdqlggvfsiv----k 307 thale cress
XP_001760387 239 LLLSGGAALGaFHLGVVRTLIEhrLLPRVIAGASVGSIICSFAATRTWTELQSFFddpmppmhffenmgsifata----h 314 Physcomitrella ...
XP_001691785  74 LLLSGGGGLGtFHIGVVKALFErqLLPRVLAGSSVGSIVCGIIATKTDAELRDLFsrldefdvgffsnsravelv----q 149 Chlamydomonas r...
CAL57958     158 LMMSGGGTLGtFHVGVARALNRkhLLPRVLAGSSVGSIVAAIIASRTQEELDEFFseenfwdllpdltffsgndpmsvmk 237 Ostreococcus tauri
EAZ29017     229 LLLSGGASLGsFHVGVVKTLVEhkLLPRIVAGSSVGSIICSIVATRTWPEIQSFFvdslqtlqffdriggifavt----k 304 Japanese rice
EEC43916     143 LLLSGGAALGfYHTGVVKTLMEnrLMPRVIGGSSAGSLVCAMIATRTDEECRTLQglvpiplrhfsavlydivtg----n 218 Phaeodactylum t...
XP_001785954 158 LVFSGHVALGtFHSSVFRTLVEhqLLPSVVVGSNLGAIVASIATTRTSSELQHFFddpsvpmdfyeklstvyvaa---yr 234 Physcomitrella ...

Feature 1                                                                                        
NP_196024    308 rvmtqgalhdirqlqcmlRNLTSNLTFQEAYDMTGRILGITVCSPRKh-EPPRCLNYLTSPHVVIWSAVTASCAFPGLF- 385 thale cress
XP_001760387 315 rlltrgavheigmlqrkmRQLIGDLTFQEAYDLSGRVLGISVCSPRKl-EPPRCLNYLTSPHVVIWSAVTASCAFPGLF- 392 Physcomitrella ...
XP_001691785 150 hlinkgslqdmsymikklRGLMGDATFLEAYERTGRILNVTVCPADTn-EPPRLLNYLTAPNALIWSAVAASSAFPGLY- 227 Chlamydomonas r...
CAL57958     238 hylrtgalhdidffqrclRALLGDLTFQEAYDRSGGRILSVCVCGTTigEKPRLLNHLTSPHVVLWSAVAASCAFPALF- 316 Ostreococcus tauri
EAZ29017     305 rvmtygalhdisqmqrllRDLTGNLTFQEAYDMTGRVLGVTVCSPRKn-EPPRCLNYLTSPHVVIWSAVTASCAFPGLF- 382 Japanese rice
EEC43916     219 rrpqdmlmndtehfracvRACVGNFTFQEAFDRTGRILNIVVTPKNNs-DPPRLLNYLTAPHVMVWSAAVASSSLPGVF- 296 Phaeodactylum t...
XP_001785954 235 lrthdakpyeieklqdsmQELLGDLTFEEAFDLSGRILGISLPACPIshLPAQFLNYLASPHVVIWSAVAVSCVPPTGLl 314 Physcomitrella ...

Feature 1                                                #                                       
NP_196024    386 EAQELMAKDRsGEIVPYHPPfnldpev--gtksssgRRWRDGSLEVDLPMMQLKELFNVNHFIVSQANPHIAPLLRLKdl 463 thale cress
XP_001760387 393 EAQELMAKDRtGHLVPYHTPpqvgpgdknmekdignRRWRDGSLESDLPMMQLKELFNVNHFIVSQANPHITPFLRFKdf 472 Physcomitrella ...
XP_001691785 228 PAQHILARNSrGEIIRFSAQstnd---------sleRRWRDGSLELDLPVQALGEMFNCNHFLVSQTNPHIVPLLNLKka 298 Chlamydomonas r...
CAL57958     317 PPQPLLAKSRnGTFVPWLPEgka-----------gpRRWRDGSLEADLPMDNLRELFNCNYFIVSQTNPHIVPLLRIKrw 385 Ostreococcus tauri
EAZ29017     383 EAQELMAKNRfGEIVPFHAPfstdpeq---gpgaskRRWRDGSLEMDLPMMQLKELFNVNHFIVSQTNPHISPLLRLKei 459 Japanese rice
EEC43916     297 EANRLVVKEA-DGWERYESGga-------------pQHFSDGSMEQDLPMQQLSEMFNVNHFLISQANPHAVMFANYQqk 362 Phaeodactylum t...
XP_001785954 315 HRPELMIKDRfDRIVPYIPPtkv----------tslEARNETSLETQIAFQQVRELFNVNHFIVSQASPYIAPWLHFKet 384 Physcomitrella ...

Feature 1                                                                                        
NP_196024    464 vrayggrfaaklahlvem-------------evkhrcnqvlelgfplgglaKLFAQEWEGDVTVVMPATl-------aQY 523 thale cress
XP_001760387 473 vrayggdfagklahlaem-------------evkhrckqvmemgfevfglaKLFAQDWEGDVTIVMPATf-------aQF 532 Physcomitrella ...
XP_001691785 299 lsrkwanvleaelkhr------------------cqvaqwllpewvpskwlMLFTQAWEGDITMTLPSAl-------wHL 353 Chlamydomonas r...
CAL57958     386 ftshgrllrfwayfiesew------------khrcrqvldlipsvdvfdvfKLFGQQWEGDATAVMWYTw-------kQF 446 Ostreococcus tauri
EAZ29017     460 vttyggrfagklarlaem-------------evkyrcnqileiglplgglaKLFAQDWEGDVTMVMPATa-------aQY 519 Japanese rice
EEC43916     363 nsvwsnpvtgfvdsiltflrdqvrtwllhlvacvgarsitpmfqtqrgigtTFLTQEYEGRSCDISLIPwlghrglfsAL 442 Phaeodactylum t...
XP_001785954 385 teersplisklvnmmeme--------------vrhrcaqvldmgirlrgltSVCAQMWEGDINIVLPITfsq----vkLQ 446 Physcomitrella ...

Feature 1                                                        
NP_196024    524 SKIIQNPTHVELqkaanqGRRCTWEKLSAIKsNCGIELALDDSVAILN 571 thale cress
XP_001760387 533 AKIITNPTPIDLrkavmqGRRCTWAKLSAIQaNCGIELMLDECVSELN 580 Physcomitrella patens subsp. patens
XP_001691785 354 SKTIVNPTTEELirnvkvGEVATWEKISAIEcNCSIEATLDKCLANIA 401 Chlamydomonas reinhardtii
CAL57958     447 SRIASNPTREFLfetatmAEKEIWPQLAAIEhAMGIELVLDECVASLR 494 Ostreococcus tauri
EAZ29017     520 LKIIQNPTYAELqmaanqGRRCTWEKISAIRtNCAIELALDESIAVLN 567 Japanese rice
EEC43916     443 LHIIYNPREAEFrewiqaAERETWRHIPAIKsHIAEEVTLDRCVQRLR 490 Phaeodactylum tricornutum CCAP 1055/1
XP_001785954 447 LHKNDDPSPDDLrkaamaGRRCTWAKLSAIQaSCSIEFKLDEYINELQ 494 Physcomitrella patens subsp. patens

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