Conserved Protein Domain Family
Nse4_C

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pfam08743: Nse4_C 
Nse4 C-terminal
Nse4 is the kleisin component of the Smc5/6 DNA repair complex. It bridges the heads of Smc5 and Smc6. This is the C-terminal domain of Nse4 that interacts with the head domain of Smc5.
Statistics
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PSSM-Id: 462585
Aligned: 172 rows
Threshold Bit Score: 57.5364
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCF50595      242 GICLFKFAVDPESFVNTVENFFHVSFLIKENKARLRTDAegnavlsiaqpPVAegeeggqegeeEGEEeGEGRSKQFIME 321 
XP_009418238  223 CVRFESLILNRTSFAQTVENIFALSFLVKGGRAEIVVGDdgqh---lvspRNSpvgk--------pgssRDVAYHHFVFR 291 
F4JET1        249 RVKIENLVLNRKSFAQTAENMFALSFLVKDGRVEITVDNngsh---fvepRNApaan--------lvlsGEVAYNHFVLR 317  thale cress
Q9C689        244 RVQLENLVLNRRSFAQTVENLFALSFLAKDGRVEIIVDKsgsh---fampRNApdan--------vvmsGEVIYNHFVFR 312  thale cress
XP_010651312  219 QVKLESLMLNRKSFARTVENLFALSFLVKDGRAEVVVDEngsh---lvspKNApaas--------svvaREVVYSHFVFR 287 
EES06447      201 SAKLENLVLNRLSFAQTVENIFALSFLVKDGRVEINIDDnghh---ivrpRNApaas--------aiasGEVSYSHFVFR 269 
EER88659      215 NARLEHLILNRTSFAQTVENIFALSFLVKDGRVQIKVNDeghh---fvypRNApaas--------dvasGNVVYSHFVFR 283 
XP_015693638  189 NARFENLVLNKKSFAQTVENIFALSFLVKDGRVEISVNNeghh---lvypRNApaas--------aitsGKVVYNHFVFR 257 
XP_002304893  235 SVRLENLILNRRSFAETVENLFALSFLVKDGRVKIVVDEsgch---fvspRNApaps--------svmsGEVAYRHFVFR 303 
XP_002957575 2308 EVQVAKLVCNHASFGQTLENLFTLSFLVRDNRVGMKKVPgagllvwaldpRRG-----------DAAGrQQKPPLQFVVT 2376
CCF50595      322 IDYQTYLETIELYRIRESVI 341 
XP_009418238  292 FDFKDWKLMLDFVAPGEELM 311 
F4JET1        318 FDYKDWEPMSKMVAVGEELM 337  thale cress
Q9C689        313 LDFKDWKLMSEMVPLGEELM 332  thale cress
XP_010651312  288 FDFKDWKLMMDLVPAGEELM 307 
EES06447      270 FDFKDWKLMKEAVKEGEELL 289 
EER88659      284 FDFKDWKLMKGVVPEGEELM 303 
XP_015693638  258 FDFQDWKLMKEMALDGEELM 277 
XP_002304893  304 FDFRDWKLMKGVVPDGEELM 323 
XP_002957575 2377 LHIDDWVKMCSRVTPEECLM 2396
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