Conserved Protein Domain Family
DUF4674

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pfam15719: DUF4674 
Domain of unknown function (DUF4674)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 126 and 221 amino acids in length.
Statistics
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PSSM-Id: 464823
Aligned: 11 rows
Threshold Bit Score: 138.764
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGI68213      28 FYMQKCKNFSNSIELPqqnfgpstACSHCGSLWSIVDHQVRIARGRKmSKSVKKIVRniKENPDQKiPKIRATLAQKSIK 107
EFX89075      34 LRCKKAVNLTNVGVKFrkvs-ksnICQSCGNPWSMGKYKLELKKTFK-TAKIQKVLK--KSKNSKK-ISSFNKHILERYS 108
XP_006635892  29 flmSQQQEKDGGLRNRl-------ICPFCFQWRLPGNHRVRFKPKQKsNLQIQKIIK--MEAAQKT-LSLKQMKILRRFR 98 
XP_012427289  32 fclylsvgNERGLGR---------ICPYCFQFLVPDSYRVRLKPKMKvTPQIEKVLK--REAKNYK-LNMKQTKLLRKYR 99 
XP_007653714  27 WTYSVSHADKKKSKD---------VCPYCFQFLVLGAYRVRLKPKPKiTPRLRKLLK--READGTRmLSFKQRKMLSRYK 95 
XP_003759615  27 WLYHSSQDEKTVSEG---------QCPYCYQFLVLDRYRVRLKPKPKlTPKVKKLLT--RESKNCR-LTFKETKILKKYW 94 
XP_002713544  27 WAYGSSHDDKSNFEE---------TCPYCFQLLVLDNSRVRLKPKAKlTPKIQKLLN--REARNFT-LSFKEAKILKKYR 94 
Q5XFZ0        27 WAYSSTHEDNSTFQE---------TCPHCFQLLVLDNSRVRLKPKAKlTPKIQKLLN--REARNDT-LSFKEAKLLRKYK 94  house mouse
ELK05659      90 WAYSSTHDAKSTFEG---------TCPYCFQLLVLDNYRVRLKPKPKlTPRIQKLLN--REARNHT-LSFKEAKIVEKYK 157
1_pfamImport   1 --------AKNTFEE---------TCPYCFQWLALDNSWVHLKLKPKlTPEIKKLLN--REAKNYT-LSFKEAKIVKKY- 59 
XP_003222293  27 WTLSNIEGKKQENAGR--------VCVFCYQLLLPGNYRVRLMPKIKiTPRIEKLLY--RERKNYR-LNLKQTKILKKYK 95  green anole
EGI68213     108 NEMNKLVIKCSVCSKNTelpfkkkNHLKPVKlnnSQMETPQSNRKKKKKKSKDKTAGLNISgyTPVLQLNKKDNNvtpti 187
EFX89075     109 ESKCNLLIKCGSCFKQT-------AFPTPLP---PKEVKSVKRIPLSSDNHEKKKCKKIKP--AAVSNQNNPGKQ----- 171
XP_006635892  99 NSTSTMLVTCYNCNKTSrqggvsrDFLTGFS---KNLNTPRSATRQKTPGLTPQSASKAS---TPLPKSASKGKS----- 167
XP_012427289 100 ESRSILLVTCKSCNKTTryygesrDFLAAKT---QNCGTPGIKSSLKTPDVKIQSAKKMTP--VSCSWLGSKGNT----- 169
XP_007653714  96 NSQSTLLITCPSCNGTIrqkgtsrSFLEALP---GSRNTPKTRPGQKVPDGKTVKSASKTNysFSHNPSNSKGSS----- 167
XP_003759615  95 DSKSILLVTCKACNKTVkydgksrSFLAEMK---NNLSTPKIQSVLKTPDIKSSGSTKKKKksFSSNKPGSQNNS----- 166
XP_002713544  95 DSKSVLLVTCKTCNRAVqhpgksrSFLSALK---SSPSTPLSKLSQEIAERRTPNA-------VNLTLSASRGKS----- 159
Q5XFZ0        95 DSTSVLLITCRTCNRTVrhhgksrSFLWALK---SNAATAANKASPKTPKRTAPGSAN-----LGQSTNGSKGKS----- 161 house mouse
ELK05659     158 DSKSVLLITCKTCNRTVkhhgksrSFLSALK---SNPTTPTSKLSLKTPERKTLSSAD-----LNHDVSGSKGKS----- 224
1_pfamImport  60 DSKSILLITCKTCKRTVkhrgkcrSFLSSLK---SKPSAPTTKPILKTPERKTLTSTK-----PNRGMSASQGKS----- 126
XP_003222293  96 ESTNVLLITCNVCGKTArhkgssrRTSW-------NKTTPASRSQPGSKRETPFSSP----------------------- 145 green anole
EGI68213     188 sPAITPKIISSNKKSIS-----PKKSKKLNIERLKRIMENKTSSKTK--NLHSF 234
EFX89075     172 -QEKLQKSKPPSKPTKVt---kPGKKQQFSRNQLKNISKTISNNASVkgSLQSF 221
XP_006635892 168 -PAGTPRSASSAPASSss--skSASAKKFAFSNLKRLLVLEENEKNKkgGLQDF 218
XP_012427289 170 -PSSLSRTRESGHATTNsa-skTPRNSKFHFSKLKRMLDLEEKEKSQkaDFKSF 221
XP_007653714 168 -LALPFRS-SSGRSTSIss-skDHNKKKQYFSQLKMLLKSEEAPKKGkgDFRNF 218
XP_003759615 167 -PALIFRTPTSGQSTPDsa-skSLSKMKRHLSQLKMMLNSEESQKTPskDFRNF 218
XP_002713544 160 -PALTFRTPTSGQSTPIcs-pkNVSRTKKHLSQLKMLLSKSESQENPkmDFRNF 211
Q5XFZ0       162 -PSLTIRTPTSGQSTPIcs-srNGSKRKKHFSQLKALLSQSASDKNPklDFRHF 213 house mouse
ELK05659     225 -PALIFRTPTSGQSTPTcs-skNTSKTKKRFSQLKMLLSQSESQKSPkvDFRNF 276
1_pfamImport 127 -PALIFRTPTSEQSTCTfssskNTSKTKKHFSQQQQ--NHQEFQKNPklDFRNF 177
XP_003222293 146 ------RISTSGQSTPGss-srTPKNAKAHFTQLKRLLCLEEEKQTNkkGLKSF 192 green anole
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