Conserved Protein Domain Family
KilA-N

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pfam04383: KilA-N 
KilA-N domain
The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.
Statistics
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PSSM-Id: 367917
Aligned: 137 rows
Threshold Bit Score: 35.3752
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001313573   23 VQFNKQLRLI-RSvKDDMYQMQSILTACy--ApdtKHTDDWFKNQSTQELLSEAQRDRLFSgsPklyenseeqrvskkpq 99 
Q3M2I6         28 ISRSLHGSPVeQRqRDGYINATALSSAYklaTgkrRDVAHWLELERTTETLNHLSSITGIP--V---------------- 89  Trichormus var...
EDN70388        7 VRDFHGNAIN-QRaSDGYFDATAMCRAA---G---KRIDNYWRLDGTQEFLSALSDNTGFPikSsgsaf----------- 68 
WP_008233440    9 EHEVQGSPVQ-QRaTDGYINATAMCRIA---G---KMWGHYRENAGNKAFLLALESDIGIPisE---------------- 65  Roseobacter sp...
CAM08690        9 PRVESGEIIP-QRmSDGYINATALCKSV---G---KSYSDYRQLQSTNHFLNELKAQTGLSeqQ---------------- 65 
Q12RF5          8 PRVEEGEIIP-QRlSDGYISATALCKSV---G---KEFGNYHALKSTQDFIAELSLQTNLPkeQ---------------- 64  Shewanella den...
ASE22815        2 SALMIAGIEI-HQdQDGRFSLNDFHRAAg--GenrHKPSLWAENQQAQELIEEIGKAG---------------------- 56 
Q4FSX7          9 PQITILDHIV-STiD-GLYSLNDLHKASg--GrvkHKPAFFLRNEQTKEIVTELQICNSP-------------------- 64  Psychrobacter ...
EDJ89885        2 SNLTILKTAI-RTfE-NLYSLNDLHIASg--AeakHQPSLFIRLDATQELISEIQKETDK-------------------- 57 
jgi:Daci_3253  36 TALTIGGTAV-RQvG-DLYSLNDLHKESg--GqskHQPHEFLRIEQTKALVAELSNSGDS-------------------- 91 
XP_001313573  100 spklyenseeqrvskkpqspklyenseeqrvSkkpqsPKThENRKNLPNGLRGWYVHRLLVNAVAMWASLRYAWYIYRLL 179
Q3M2I6         90 -------------------------------I------ELyQSFRGSPENGGGTWIHPKLAVRFGIWLSDEFGYQVEQWV 132 Trichormus var...
EDN70388       69 --------------------------pqksvTeq--nQVLiQIIQGGNPENQGTWIHPQVSVNLAQWCSPQFAVQVSEWV 120
WP_008233440   66 -------------------------------L------VK--SVKGGDPRVQGTWVHPQVAIHLAQWLSPEFAVKVSKWV 106 Roseobacter sp...
CAM08690       66 -------------------------------L------IQ--QRIGGEPSLQGSWVHPYLAINLAQWLSPAFAVKVSTWV 106
Q12RF5         65 -------------------------------L------IH--IIRGGNAQQQGTWVHPYLAINLGQWLSVKFSVKVSQWV 105 Shewanella den...
ASE22815       57 ---------------------------------------IpALRVARGGRAAGTYACKELVYAYAMWVSPVFSLHVIRTF 97 
Q4FSX7         65 ---------------------------------------EeVLRVQRGGTNQGTWVCKELVYSYAMWISAKFHIAVVRTF 105 Psychrobacter ...
EDJ89885       58 ---------------------------------------EnILQSFRSGVNRGTYACEELVLAYAMWISPKFHLIVLRAF 98 
jgi:Daci_3253  92 ---------------------------------------RnYLETKRGKYG-GTYACKELVIAYAAWISAKFHLKVIRVF 131
XP_001313573  180 DEIHRQ 185
Q3M2I6        133 EEWVLK 138 Trichormus variabilis ATCC 29413
EDN70388      121 FELMTT 126
WP_008233440  107 YDWLSG 112 Roseobacter sp. CCS2
CAM08690      107 HEWMSG 112
Q12RF5        106 YEWQTG 111 Shewanella denitrificans OS217
ASE22815       98 DSAAAN 103
Q4FSX7        106 DALITR 111 Psychrobacter arcticus
EDJ89885       99 LAMHRN 104
jgi:Daci_3253 132 LAVTTP 137
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