Conserved Protein Domain Family
TDRP

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pfam15683: TDRP 
Testis development-related protein
TDRP is a family of proteins found in chordates. It is predominantly expressed in the testis. distributed in both cytoplasm and the nuclei of spermatogenic cells. It may act as a nuclear factor with an important role in spermatogenesis.
Statistics
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PSSM-Id: 464801
Aligned: 13 rows
Threshold Bit Score: 148.034
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_008116605  65 GAGFRGWKEVTSIFNKEDEQQLLTGSKSPKSKGTSLKLKEDV-------KSEKKPGFWDS--LVTKQNITSRKPDEIEGW 135
NP_001016270  49 GASFRGWKEVTSIFNKDDEQQLLKGAKCPKSKVISVKPKEDV-------KTEKKAGFWDS--LAIKQNIQPKKADEIEGW 119
XP_006005366  49 GASLRGW---TSLFNKDDEHQLLTGSKPPKGKGNNLKLKEDV-------KGEKKPGFWDS--LVPKQTSQSKKADEIEGW 116
XP_015213780  46 GKKAKAKKEKKPIIIEDDEHFLLTGVTPVNRKGSNKKKEEEKsk----mYVEKSYCFWETvtMTMKQITPTKKLDKIEGW 121
XP_002685209  38 GATFRGWKEVTSLFNKDDEQQLLEGRKSPKSRATNLRLKEEL-------KTEKKSGFWDN--LVLKQNIQSKKPDEIEGW 108
XP_012919076 137 GASFRGWKEVTSLFSKDDEQHLLERCRSPKSKGTNLRLREEL-------KTEKKSGFWDN--LVLKPNVQPKKPDEIEGW 207
ELK10071       3 GASFRGWKEVTSLFDSEDEQHLLGAPESPRSQGTHLRPREEP-------KTEKKSGFWEH--LALKQNTQPKKPDEIEGW 73 
XP_008249795  98 GASFRGWKEVTSLFNKDDEQYLLESRKPPKSRGANSRLKEEL-------KTEKKSGFWDS--LVLKQNTQSKKPDEIEGW 168
XP_013217874  11 GAGFRGWKEVTSLFNKDDEQHLLERCKSPKSKGSNLRLKEES-------KTEKKAGFWDN--LVLKQNMQSRKPDEIEGW 81 
Q498E2        35 GASLRGWKEATSLFNKDDEERLLETSRSSKSKGTNVRLKEEL-------KAEKKSGFWDA--LVLKQNVQPKKPDQMEGW 105 Norway rat
XP_003271426  51 GASFRGWKEVTSLFNKDDEQHLLERCKSPKSKGTNLRLKEEL-------KAEKKSGFWDN--LVLKQNIQSKKPDEIEGW 121
XP_031177672  57 IMSKKEKREKKMFSSKDDEHFLLTGVKLADRRGSHKKIKDDEkekekkdKPDKGHCFWESvtMTMRQISPTKKLEKMEGW 136 pikeperch
XP_016284195  67 GASFRGWKEVTSMFNKDDEQQLLEKCKSPKFKGTNLRIKEDV-------KTEKKSGFWDS--LVLKQNVQSKKPDEIEGW 137 gray short-tail...
XP_008116605 136 EPPQI---------PAGDPLSD-AGNAL----ND-----YSSWS--GWEDETkgsTKYTNLASSGN-SS--RWSIKSAGK 191
NP_001016270 120 EPPHI---------TVEESPSF-PDDVL----DD-----PNSWP--GWEDETkgsTKYTNLTSSGN-SS--RWSIKSAGK 175
XP_006005366 117 EPPQI---------IVEDTTAD-TENHQ----TD-----SASWS--AWERDPkgsSKYTNLVGSGStSS--RWSIKSAGK 173
XP_015213780 122 EPPQVt-------dVIEEHTAR---DALtf-pTE-----PSSWP--GLEEDT---SNYSNLTDPKNsGP--KWSTKAKEK 178
XP_002685209 109 EPPKL---------ALEDVAAD-SGGPV----SD-----RVSRP--GWQEDTkgsSKYTSLAGAGS-SS--RWSLRSAGK 164
XP_012919076 208 EPPAL---------ALEEVTAD-AGDTA----SG-----RPPQP--GRESDSkgcRRYSSLASSGN-SS--RWSLRSAGK 263
ELK10071      74 EPPKL---------ALGNMAAE-AGDTV----TD-----CPSRP--GWEPGAkgsGGYSSLAGSAH-AS--RWSLRSAGR 129
XP_008249795 169 EPPRL---------ALEDAAAN-SGDAL----GS-----CPPWP--EWEDATkgsTKYTSLASSGG-SS--RWSLRSAGK 224
XP_013217874  82 EPPQF---------AVEDAAAG-MGDSV----HS-----QQLWT--GWEGEDkgsIRYSSLTSSAS-SA--RWSLRSAGR 137
Q498E2       106 EPPKL---------TAEDVATDhTEDGI----SS-----LPPWS--AWEDDTkgsTKYTSLASSAS-SS--RWSLRSAGK 162 Norway rat
XP_003271426 122 EPPKL---------ALEDISAD-PEDTV----GG-----HPSWS--GWEDDTkgsTKYTSLASSAN-SS--RWSLRSAGR 177
XP_031177672 137 EPPHLenltetvtdEAPEDKSQkGGLPVsfpdSLglpleLASWAgqGLEEDS---SRYANLSDSKDsTAavRWTARAKVK 213 pikeperch
XP_016284195 138 EPPQI---------TLEDPVTD-LGDSS----RD-----HLSWP--GWEDETkgsTKYTNLTSSGN-SS--RWSIKSAGK 193 gray short-tail...
XP_008116605 192 LVSIRRQSKGNLTDN-WEELE 211
NP_001016270 176 LVSIRRRSKGNLTEN-WEELE 195
XP_006005366 174 LVGIRKRSKGNLTDD-WEELE 193
XP_015213780 179 LAGMRRRSRGNVSEI---LEG 196
XP_002685209 165 LVSIRRQSRGHLTDD-WEELE 184
XP_012919076 264 LVGIRRQSRGHLTDK-WEELE 283
ELK10071     130 AVSIRRQGRGHLMGD-WEELE 149
XP_008249795 225 LVSIRRQSKGHLRDG-WEE-A 243
XP_013217874 138 LVSLRRQSKGHLADA-QEEVE 157
Q498E2       163 LVSIRRQSKGHLTET-CEEVE 182 Norway rat
XP_003271426 178 LVSIRRQSKGHLTDS-PEE-A 196
XP_031177672 214 LAGISRMSRGIVSESaWEGFK 234 pikeperch
XP_016284195 194 LVSIRRQSKGNLTdnweele- 213 gray short-tailed opossum
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