4II1,2CQE,5GM6


Conserved Protein Domain Family
zf_CCCH_4
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pfam18345: zf_CCCH_4 
Zinc finger domain
This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.
Links
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Statistics
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PSSM-Id: 465719
Aligned: 278 rows
Threshold Bit Score: 24.685
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4II1_A        79 CPFFLE-GKCRFKENCRFSH 97  
PDM66893     137 CKHYLK-GICTWGEQCNFAH 155 
ETW82744     216 CKHFTLlGRCPLGNACNFVH 235 
EXB33953      92 CAKFKM-GMCRNGENCNFAH 110 
VDD84398     127 CFHFLRrGTCPKGEACKFAH 146 
OAJ41084      64 CTHFIR-GACRQGSSCPFQH 82  
KCW50043     547 CRHFLK-GSCNRGSNCSFSH 565 
XP_018678977 124 CYYFQR-GQCLKGERCPYTH 142 
OWR47313     952 CIYFQRkGSCRQGENCTFLH 971 
XP_008611593 534 CRDFQG-GSCRFGDRCKFSH 552
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