2A1S_C          3 IIRSNFKSNLHKVYQAIEEADFFAIDGEFSG-Isdg-----psvSALTNGFDTPE----ERYQKLKKHSMDFLLFQFGLC 72   human
PDM80757        4 VCNSNFREWFPELIKVIDSAAFFAIDLEFLG-Lpss-----ardDLVPTLFDESE----QRYKKIVQSVRRYPPCQLGIA 73  
PDM66046       22 ITCNNFKEKHGYIETVIRNASFAAIDLEFLG-Lede------evDMKCSLFDSTQ----ERYEKSLHSVRRFPPAQLGVA 90  
7_pfamImport    1 ITDANFLQYAPQLRESILCSDFIAIDFEFFG-Ld----------TDAISLHDTIE----TRYCLLRNNVIKYRPCQLGLS 65  
Q21412          4 VTDSNFLDAAGTLRKGLLYCDFVAIDFEFLG-Ld----------VSAISLHDTVE----SRYQILRDNVIKYRPCQLGLT 68   Caenorhabditi...
EGT43616        4 ITDSNFLELSPKLRKTLLYTDFVAIDFEFLG-Ld----------TTAISLHDTAE----SRYRILRENVIKYRPCQLGLS 68  
XP_003114320    4 IKDSNFLELAPKIRKTLLHSDFIAIDFEFLG-Ld----------SSAISLHDTAE----ARYRILRENVVKYRPCQLGLS 68  
CAP28460        4 IKDSNFLELAPQLRKTLLQSDFVSIDFEFLG-Ld----------TTAISLHDTAE----KRYEILRANVIKYRPCQLGLS 68  
EDN97606      116 VWKGNLHEEMAILRQLVDKYPYISMDAKFPGiV--------------ARPMGSFNgrgdYHYQCLRCNVDLLKLIQLGIT 181 
EPS38216        3 VTRANFKDQLPEILKLIEESEFIAFDFEYSG-LlsehgrgpfpgKIERGRKPTME----ERYQLSKESAERYCIFQMGIC 77  

2A1S_C         73 TFkydYTD-SK---------------------------YITKSFNFYVFPKPfnrsspDVKFVCQSSSIDFLASQGFDFN 124  human
PDM80757       74 VFterDDGaS----------------------------YEVESFAIPLFKRLp----hKQVFSYSLSAVSFLANNNFDFN 121 
PDM66046       91 FFtalDDGeR----------------------------YKVDVFTFYLFQSis----mGRDYSFSIASLSFLSEHGFNFN 138 
7_pfamImport   66 IF---KQM-KNg-------------------------sYVADTYSIPLLRRTg-----PSDSLLNTKSMRFLMNHELDLR 111 
Q21412         69 LF---KQK-SNr-------------------------aYKADTYSVPLFQRFg-----DNDTSISLPSMRFLVKNKFNLN 114  Caenorhabditi...
EGT43616       69 FF---KQT-SNl-------------------------gYKADSYSIPIFQRFg-----DPDTKVSFSSLRFLRNNKFDLN 114 
XP_003114320   69 FF---KQT-DNl-------------------------gYKADSYSIPLLQRFg-----DVDTKVSFSSLRFLLNNKFDLN 114 
CAP28460       69 FF---KQK-SNk-------------------------gYKADSYSIPLCQRFg-----ASDTSISVNSLRFLLENNFDLN 114 
EDN97606      182 LFsedGESlPAtphsdsgldrnsagrrigngvvqvpctWQF-NFKFSLS-----------DDMYAEKGIDERKAAGTDFS 249 
EPS38216       78 CLtwdTKSnR----------------------------YLGRPFNFYITPAVipslhyDRNFSATGDAMAFHSKHGFDFN 129 

2A1S_C        125 KVFRNGIPYLNQEEERQLREQYDEkr-----sQ---Ang-----------aG--Alsy----------------vspNts 167  human
PDM80757      122 KFIMEGVTYSNGRQTEDMRKEILSggidydvfEdglEh-------------R--L----------------------Q-- 162 
PDM66046      139 KLTREGISHMNLDELQRVLERFHQpn----giEifgAq-------------M--P----------------------P-- 175 
7_pfamImport  112 QIFAEGVEYCNRSELKAFQRALKSg----------eLlssigkenvgkiecLkvMllekiyqanselithsteefipPsp 181 
Q21412        115 QVFMDGVEFCTRKEFKKFERALLAg----------tAasylsrevksqielLkvMvhekcyqstsyhithrtdepmqKip 184  Caenorhabditi...
EGT43616      115 QVFSEGVEYCTRAEFQNFDKALKEd----------tAlrsvskeiqlqielLkvMlhekcyiaetdmitnsteepmqEvr 184 
XP_003114320  115 QVITDGVEFCRRAEIRKFEIALRKg----------tAtsyiskdiqlqielLkvMlhekcyrvelekitnstiepmqDpn 184 
CAP28460      115 QVITDGVEFCTRAEIKKFEEALSKg----------tAlsyiskdkqmkveqLkvMlhekcfrvkaemithtteepsqDcr 184 
EDN97606      250 RLKEEGI------DPFEF-------------------------------------------------------------- 261 
EPS38216      130 RLFGQGCTYLSHSEEVLVRDIRRLhe---------eDl-------------E--Nd---------------------V-- 162 

2A1S_C        168 -----------kcPVTIPEDQ-KKFIDQVVEKIEDLLQSEENKNLDLEPCTGFQRKLIYQtl------------------ 217  human
PDM80757      163 -------------ILKINFQRaAQNAIRMSQHTVHRSPSARSYQTGLQLPHPILIELVRSgefidtdtvdqtmhppwdrp 229 
PDM66046      176 -------------LFHHLTRIiRSEVAKLRRGSAGSEGAPQHTFPGLPIAISQKLN------------------------ 218 
7_pfamImport  182 alnprssialkmpGAKKSTFEiCVFIYEMTKSFPQFQFSVDE-------------------------------------- 223 
Q21412        185 lkmkpnssvslrmPRNLSSVEkYMIIYELTKAFPQFLFTCDEK------------------------------------- 227  Caenorhabditi...
EGT43616      185 fslignkpvslkiTQGLCCVEiCMIIHELTKAFPQFTFKMDE-------------------------------------- 226 
XP_003114320  185 lkvahnkpvslkvPSGFSSVEiCMVIHELTNAFPQFVFKFNS-------------------------------------- 226 
CAP28460      185 liinsdkpvslkmPAGLCSVEtYIAIHDITNSFPHLLFSLNE-------------------------------------- 226 
EDN97606          --------------------------------------------------------------------------------     
EPS38216      163 -------------YVDEGE---GSMLKAALKQIQAWDAERDGDTAAFLNIIPLETDRVFNayqr---------------- 210 

2A1S_C        218 -----sWKYPKGIHVETLETEKKERYIVISKVDEEERKRREQQ---KHA---KEQEELNDAVGFSRVIHAIAN--S-GKL 283  human
PDM80757      230 lsplekAVIEYVFTNDHRHLEFSISHDGTLLYVAELPVLTLLHyseEEWveeKLEKLLQEISGVSEIVKRML---ArRVP 306 
PDM66046      219 ----------DLQRAALLYKLHGCTPGIRCELQDQILMVYPSSeppRDIkkrLFERVCAEMSGVSDVVMAII---ErKLP 285 
7_pfamImport  224 ------------------------QKFSLIVNNLPNMIDRNEN---LKH---AQNKCLEAFVGISAIMETAML--K-RKL 270 
Q21412        228 ------------------------QQNLHVKNISDDYLKEKDN---LER---ARARCSESVKGVSAILQVVHM--T-GKL 274  Caenorhabditi...
EGT43616      227 ------------------------KNCALKVSNKPEFTTEAEN---INQ---TRVRCSEAFEGISAILEAVMM--M-RKV 273 
XP_003114320  227 ------------------------QNSTLNVAMLPEKMTETEN---KNQ---TRLRCSESFEGISAILEAAMM--M-RKV 273 
CAP28460      227 ------------------------KDKSLDVTMLPETMTETEN---KKQ---TRMRCTESFEGISAILEAAMM--M-RKV 273 
EDN97606      262 --------------------------------------------------------------GAVLISSGLVCdeE-KRW 278 
EPS38216      211 ---rllHQLLRNKFPHLIGQSYDKHFQVQPKIEDREVAR-------AKVrdeHFEALLKEQRGVRIIIDKIKE--L-KKP 277 

2A1S_C        284 VIGHNMLLDVMHTVHQFYCP-LPADLSEFKEMTTCVFPRLLDTKLMAST------------Q----PFKDIiNNT----- 341  human
PDM80757      307 IVGHNSFLDLVYLYECFVDD-LPDSYEDWKAATRKEMPTVFDTKIIACLl----------kNq---LSENGvMDH----- 367 
PDM66046      286 IIGHNSFRDLLYIYEYCIAD-LPDTLEEFKRLAMSVFPFVADTKILAE------------------ECKNRlSVHgvm-- 344 
7_pfamImport  271 IVGHNSLLDFIYMYHYFFET-LPESYDDFKRIFHKLCPKVVDTKVLALMlrt------eipEv--dN------------- 328 
Q21412        275 VVGHNSLLDAMYMYHYFFSH-LPANYQMFKDKFNALFPRIMDTKLLAQAlrf------elpGv--gD------------- 332  Caenorhabditi...
EGT43616      274 IVGHNSLLDTMYLYHYFFER-LPEKYQTFKRKFSALFPKVIDTKILAQVlrl------elpGv--gD------------- 331 
XP_003114320  274 IVGHNSLLDAMYLYHYFFAP-LPQNYNAFKRQFHGLFPKIIDTKLIAQSlri------elpGv--gD------------- 331 
CAP28460      274 IVGHNSLLDAMYMYHYFFSS-LPLKYRNFKREFNSLFPKVIDTKILAQViri------dlpGv--gD------------- 331 
EDN97606      279 ISGHAGY-DFGYLTKIMLQRaLPDDEREFDMLMKKFFPSVYDIKYLMQQgtimsklgqlshVdavtA-----ELLqrner 352 
EPS38216      278 LVGHNCFGDLCYWIRMFDGS-LPATLGEFRQLLRKDFGLIIDTKFLAMNmd--------rkLy--gE-----ISS----- 336 

2A1S_C        342 --SLAEL---------EKRLKETPFNP----PKVESAEgFPSY-DT-----ASe----qLHEAGYDAYITGLCF 390  human
PDM80757      368 --SLKTL---------GAFFESASCGQilpfS-------YPSI-SEgpcsqYIfgvgehFHNAAFDARVTGSIF 422 
PDM66046      345 nyRLESL---------NAFF-------------------ESC--FVl----LRtt--ksMHDAGVDAVSTGQSF 382 
7_pfamImport  329 --SLEHLgnffhsdraDRMVPPEIRGAi---KLWTHNGnTEEF-DQ-----KS------YHDAGYDAYITGSVF 385 
Q21412        333 --SLENLgdyfgsdksDKTVPPELRGF----IEPWMNP-LEDE-SE-----NV------YHNAGFDSYVTGEVF 387  Caenorhabditis elegans
EGT43616      332 --SLERLgdyfgteksNKTVPPELRGY----IGPWMNP-LDDD-SE-----NV------YHNAGFDSYITGEVF 386 
XP_003114320  332 --SLEKLgdyfgteksNKTVPPELRGY----IGPWMNP-LDDD-SE-----NV------YHNAGFDSYITGEVF 386 
CAP28460      332 --SLERLgdyfgteksNKTVPPELRGY----IGPWMNP-LDDD-SE-----NY------YHNAGFDSYITGEVF 386 
EDN97606      353 hpNLEAM---------IDVL-----------KV------K----R-------Lg----aIHQAGSDSLVNGRVF 385 
EPS38216      337 --GLQEL---------VNKL-----------GNQNLP--RVEVpVGac--nYDng--trDHQAGCDSWNTARAL 382