5LGD


Conserved Protein Domain Family
CD36

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pfam01130: CD36 
CD36 family
The CD36 family is thought to be a novel class of scavenger receptors. There is also evidence suggesting a possible role in signal transduction. CD36 is involved in cell adhesion.
Statistics
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PSSM-Id: 460076
Aligned: 208 rows
Threshold Bit Score: 283.71
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5LGD_A        14 VIGAVLaVFGGILMP--VGDlliqKTI-KKQVVLEEGTIAFKNWVKTG--TEVYRQFWIFDVQNPQEVM-MNSSNIQVKQ 87 
XP_003244734  73 ILGFVLsLFLTIFIWftDLY----TNElYKRLTIQNGSLLYDSWKEPP--VRPLMCVYIFNYTNVNEYMsGMHQKLKVQE 146
EFN70524      42 FVSFYV-F------WytDTF----SNLvFSQMKLQNDTRSFNLWQHPP--VKLEYRVRIFNYTNVREFEtGMASKLRVQE 108
XP_011136608  40 FGTFYI-F------WytNYL----QDYvYSQLQLRNGSYAMSMWQNPP--MKIYFKVHVFNYTNTEDFLaYRADKLRVEE 106
XP_001948133  78 GIFTII-M------WftEFY----MFQiLQFVTITQGSASYNMWQNPP--VKPYVSIYPFNYTNINRVLkYGDTPI-VQE 143
EFA05669      70 LTGVVA-M------WftDMF----DNAvFANLAIIPDTQSYDMWVKPSp--kPLLKVHIFNYTNVPEFEsRDDEKLNVKE 136
XP_002015689  98 VTGFFV-M------WftEFY----NNTmLENLVLAENSDTAKSWLNPDpkYDTLLKAHIFHYPNIEDYLaGRADKIQIRD 166
XP_015029122  87 VTGFFV-M------WftEYY----NNTmLKNLILAENSETANSWLQPDpkYDTLLKAHIFNYTNIEDFLaGRADKMHVED 155
XP_002062802 107 VTGFFV-------MWf---TefynNTMlE-NLILAKDSETVKTWLNPPskYDTLLKAHIFHYPNIEDYLaGRADKIKIED 175
ETN64883      71 AIGFII-M------WftDVY----NNSiLEKLILAPNTTAAEWWVTPP--VFPLLKVHVFNYTNTREFLkGEDSKLRVED 137
5LGD_A        88 RGPYTYRvRFLAKENVTQDAeDNTVSFLQPNGAIFEPSLSVGt--eADNFTVLNLA-VAAASHIyqNQFVQmil-nslIN 163
XP_003244734 147 VGPYCYR-ETLYRVNITDHk-NGSQTFNEMKVQEYAYDASNGt--dNDIIIVPDIPlISAIALTieENFIIrnamssfLN 222
EFN70524     109 LGPYVYR-ETKDRVNVVMHe-NGTVTFQEKTSYVWA----DGss-eNDVVVVPNVPmMFIVAFVrdSSFAIrfltntvLS 181
XP_011136608 107 VGPYIYL-ETKNRVNVEVGe-D-TITYQDSKSYEWV----GGrseiDDKIVVPNMMmILTSSYVhkLPFVTrlslaalST 179
XP_001948133 144 LGPFVYR-ETVERLNVEFNa-NGTVTYQERRSNEFVPEMSQGdp-eRLTITVPNLPlISAISKTadTFFFTqkvmsllLN 220
EFA05669     137 VGPYVYE-AALERVNSKFDg-SH-VSYQEQRVYKFMPELSIGrk-qNDRVIVPNIPlFTAASLNkhSTFLTrvgisslLN 212
XP_002015689 167 MGPLVYQ-EHTVKDEVSFNk-NFTVTFRDRKSYKFLPEKSAIr--eDDVLLVPNVPlISAAGHVkrMPYATrlisgmlIN 242
XP_015029122 156 LGPLTYQ-EHTVKDQVSFNk-NHTVTFRDKKSYKLLPEKSTLr--eDDVVLVPNVPlLSAAVHVkrMPAFKrllvtgtIK 231
XP_002062802 176 LGPLTYQ-EHTVKDEVSFND-NNTVTFRDHKSYKFLPEKSSIr--eDHMVLVPNIPlLTAAVHVkrFPMFErlsvawiIK 251
ETN64883     138 LGPFVYK-ETAQKIDVRHNg-DGTIAYREHRHIEYLPEESHGn--pFDEVVVPNVVlLSAEMKKlnLGTFEkfvyggvKG 213
5LGD_A       164 KSKSSMFQVRTLRELLWGYRD-------PFLSLVpyp--------vttTVGLFYPYNNTADgvyKVFNGKDNISKVAIID 228
XP_003244734 223 HVSNSPFVTVSVYDFCFGYQDdviralaTMAKLAnkai-------pfeKFGLLIKRIGVNPdrlTVINGLDNLNQMGQVI 295
EFN70524     182 TLRERTFINVTAGGFLWGFDN-------SLFHMVkpflmfk-rdisfdKFGLLVTKSGVNKnyiTMNTGSQDLHNLGMIE 253
XP_011136608 180 SLNQRPFLHLNTADYFWGYDD-------SLFDIMkpfvnfq-qdtqmeKFGLFVTKQGINSnriTINSGTKDMKKLGRYE 251
XP_001948133 221 GFMVKPFLDLKINDYFWGYED-------SIYTFAqslastvhrdahlsKFGIITGRRGVSPnqiTIHSGVGNLNELGIIT 293
EFA05669     213 SLNAKPFLSLPAHRFIIGYED-------NLYALSksymkfq-nqkpyeHFGLVSSNAGIRDdvvTINTGASDINKIGLIE 284
XP_002015689 243 TFNEPLFKNLTAAEYLWGYED-------KIIKLkslg-------kgkrRFGLLMSRNGTSVdsiQVNTGEDDITKYSTIT 308
XP_015029122 232 LFEEPLFKRLTAHEYLWGYRD-------KIISLeslg-------ggktHFGLLKTRNGTSVdsvQLNTGEDDISKFSIIT 297
XP_002062802 252 QYREPLFKNLTAGELLWGYED-------KIIKLkslg-------mgkrRFGLLMSRNGTSVdsvQLNTGESDINQYGIIT 317
ETN64883     214 SAGASAFMRTSTDSFLWGYDD-------KLLGKLktflp----kdtpdRFGMLMSRNGTGAenfTIYSGESSLQHLAIIK 282
5LGD_A       229 TYKGKRNL-SYWEsh-cdMIN-GTDAASFPPF-VEKSQ-VLQFFSSDICRSIYAVFES-DVNLKG-IPVYRFVLPSKAFA 301
XP_003244734 296 QLNGKSMLhPWSTde-cnSVG-GSDGMFFPRLkIQQGE-TIHLFHKDSCRKLPLTFHSkEKIKNG-VIGHRYSLSINSFN 371
EFN70524     254 RVNGINNRkIWGDek-cdRIM-GSDGSMFPPYlIKNTSePLYMYSHELCRNLPLHFAEqVITHG--IPSLRYKLTPNAFN 329
XP_011136608 252 QINGHTSSnIWGDkr-cdKIE-GTDGTFFSPYlLNNRNnTLEMYSSEMCKSISYEFTEpVTHHN--ILTWRYKLSPNTFE 327
XP_001948133 294 RYNGLDALdVWKTde-cnRLD-GSDGSQFPPTtLSRKS-KLFVFHMDLCRRFPLVYKEdIETVPG-VTAFRFQAPRNVFD 369
EFA05669     285 SFNGEPALnFWSTae-cnDISaATDGTLFSPRlVRNKR-PIQFYLKEMCRPLPLHFKEeVKILNGkIPAYRYTLPENVFD 362
XP_002015689 309 QFNGMPQLdYWEGee-cnRID-GVDPSMFSPNlLQTRD-TVHVFLQVLCRKVPLNFEKeVTIYDD-IDVLRYRTPMDVFD 384
XP_015029122 298 QFNGKPQLdFWQGde-cnRID-GSEPSMFSPIeLQTRN-TVYVFLQVLCRKVPLHFEKeETIYND-IDVLRYRTPLDVFA 373
XP_002062802 318 QFNGMPQLg-fWEgdecnRVD-GSEPTMFSPNlLQNRD-TVNVFLQVLCRKVPLHFEKeEIIFND-IDVLRYRTPLDVFS 393
ETN64883     283 ELDGSTRLhQWHTde-cdLVG-GTDGSQFPPHlMDRQA-TLQVFIKSLCRKFPLVYDSeVTALEG-IPAWRYKIPPTVFQ 358
5LGD_A       302 spvENPDNYCFCTEkiisKNCTSYGVLDISKCKEGRPVYISLPHFLYASPdVSEPIDGLNPNEEeHRTYLDIEPITGFTL 381
XP_003244734 372 ns--iPENRCYCTS----TPCMPDGIFDMGKCSTRSPVVVSRAHFLHSDPsLLDAVEGLNPDPKkHEFLWLIDPILGITM 445
EFN70524     330 lsdT--QNKCFCPKvnglRVCPPAGLFDVSACNDGVPLLSSFPHFYGADKsLLEQIDGLNPRQEdHESYIDLHPRIAVPM 407
XP_011136608 328 ftkE--QSKCYCQKegtsRSCPRRGLFDTTRCS-NMPILLSHPHFFRAEEsLMEKLDGLHPRAEeHDSYIDVHPDIAIPM 404
XP_001948133 370 tpnTNPDNDCYY-Ts---ENFPPSGVFNSSPCN-GAPVMMSFPHFYLGDPeLRRDILGLSPDPElHETFVDVHSKLGVSL 444
EFA05669     363 tpeRTPSNQCYCDLd--lGECPLQGVFNATPCTFGAPIFMSFPHFHNADPaLKEGVTGLNPDSv-YETYADLHPTLGFVM 439
XP_002015689 385 hpsENPANQCYCHNt---ERCLPSGVINATKCYGDSPIFPSFPHFFSGDPvLYKIFDGIKPDAElHQTYADIHPRFGFPI 461
XP_015029122 374 hpsENPANECFCKNt---DRCLPSGVINATKCYDDSPIFPSFPHFFSGDPvLYKDFEGIKPDADlHQTYADIHPRFGFPI 450
XP_002062802 394 hpsENKANECYCKNv---DICLPSGVINATRCYNDAPIFPSFPHFFSGDPiLYKDFDGIQPNAElHQTYADIHPRFGVPI 470
ETN64883     359 hpsVHKQNECFCPQe--pKKCSPSGLFNITGCSMGAPIFASFPHFYTGDQlLIDTIDGIEPVQEkHETFADIHPRLAFPI 436
5LGD_A       382 QFAKRLQVNLLVKPSEKIQV-LKNLkRn-YIVPILWLNE---TgtIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMF 456
XP_003244734 446 ETQMRIQLNIQVRNPHGYGS-LAKI-PdnTILPFTWLEIktgD--VSPKLSMLLFHLTFTVHWLQTFLMCLSLV-GLLGT 520
EFN70524     408 AGWSRMQINLKVRKAIGVPF-LGNL-KdgTILPLIWIEVgv--dkVPEFILDIFQTAYFTVTNVEMALQWGSLI-VMMLS 482
XP_011136608 405 AGWMKLQINVEVRKGPGQPQ-LGRL-QngMILPLLWIDVgvdDtdFPQNVLNMFYMVTFTLHVIEAAVQWSSLV-GMVLS 481
XP_001948133 445 GGRSRFQVNVLLKKVDGISH-FKNF-KqgIILPVAWIEVkvdK--LPDDIKRSLQQTSISINLGEILLKWTSLL-TLTLS 519
EFA05669     440 AGKNRIQVNVQVAKAFGISQ-VNMF-EdgLMLPVAWIEYvleDktLPDDMISIIFQTTFTLRSVELGLKYGCILSTGVTL 517
XP_002015689 462 SGASRVQINIMLDKTPLLKNqGDRL-EngTILPLMWIEItsgD--FSEEILHMLYVSTFYLDAIQQSLKYGTLL-ISVTS 537
XP_015029122 451 SGASRIQINIMLDKTPLLRNqAARL-EnaTILPLIWIEItagD--FNDDVLHTLYVSTFGLDAIQLALKYGTLL-VSVTT 526
XP_002062802 471 SGASRVQINIMLDKTPLLENkANRL-RnsTILPLMWIEIt--SgeYSEDVLHDIYFSTFGLDAIQLALKYGTLLISVTSF 547
ETN64883     437 GGASRFQINIRVQ-----PG-MEMF-KqeLYLPVIWLEVvpgE--ISDELRTMIYHSTYSANAIQMSLKIGSLA-IFALS 506
5LGD_A       457 VAFMISY 463
XP_003244734 521 SFCLMRM 527
EFN70524     483 LSALVTY 489
XP_011136608 482 IGALLVC 488
XP_001948133 520 MVFLVRK 526
EFA05669     518 FCILMIL 524
XP_002015689 538 FSLIVAG 544
XP_015029122 527 FSLIVAS 533
XP_002062802 548 SLIVAGV 554
ETN64883     507 FVLVVAK 513
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