Conserved Protein Domain Family
VGPC1_C
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pfam16799: VGPC1_C 
C-terminal membrane-localization domain of ion-channel, VCN1
VCN1_C is the short C-terminal region of voltage-gated proton channel 1 proteins in higher eukaryotes. The domain is necessary for achieving the dimeric architecture, two monomers form a dimer via parallel alpha-helical coiled-coil interaction. but it is also essential for localising the protein to an intracellular membrane.
Links
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Statistics
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PSSM-Id: 465275
Aligned: 6 rows
Threshold Bit Score: 79.6022
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ELW65529     568 QQLLRLKQMNIQLAAKIQHLEFSCSEKGSLSDchiPLMKLKSSIGLLLQQE 618
XP_016779696 226 RQLLRLKQMNVQLAAKIQHLEFSCSEKEQEIE---RLNKLLRQHGLLGEVN 273
XP_007653833 369 QQLSRLRQANLQLVAKVQHLEFSCNEKEQEIE---RLNALLKQHGLI---N 413
XP_015130784 188 QQVSKLKQVNLKLATKVEQLQHSCVEKEQEIE---RLTRMLKQHGLLSEQT 235
XP_016157803 189 QQVSKLKQANLKLATRVEQLEHSCLEKEQEIE---RLNNILKQHGLLIQQK 236
XP_007489906 235 RQLSRLKLINHQLATKIQHLEFSCTEKEQEIE---RLNKLLRDHGLL---E 279 gray short-tailed opossum
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