3RU6,4MUZ,1VQT


Conserved Protein Domain Family
pyrF
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TIGR01740: pyrF 
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orotidine 5'-phosphate decarboxylase, subfamily 1
This model represents orotidine 5'-monophosphate decarboxylase, the PyrF protein of pyrimidine nucleotide biosynthesis. In many eukaryotes, the region hit by this model is part of a multifunctional protein. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis]
Links
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Statistics
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PSSM-Id: 273785
Aligned: 15 rows
Threshold Bit Score: 215.297
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3RU6_A  27 LCVALDLSTKEECLQLAKELKNldI--WLKVGLRAYLRDG-FKFIEELKKvDDf---KIFLDLKFHDIPNTMADACEE-- 98  Campylobacter jejuni ...
Q8PV88   7 MILALDVTEREEALKIAENVREfvD--AIKVGYPLILATG-LDIIRELAR-FA----PVIADFKVADIPNTNRLICEQ-- 76  Methanosarcina mazei Go1
O29333   4 LILALDVMDGEKAMEIAKKVAEhvD--RIKVNYPLVLSAG-VGIMKRLSEiK-----PVIADFKIADVPYTSSLIARI-- 73  Archaeoglobus fulgidu...
Q9PIC1   3 LCVALDLSTKEECLQLAKELKNl-Di-WLKVGLRAYLRDG-FKFIEELKKvDDf---KIFLDLKFHDIPNTMADACEE-- 74  Campylobacter jejuni ...
Q92SN8   9 LIVGLDLPTVTEAEKIVSTLGe--EvlFYKIGYQLAFAGG-LDFARDLAAsGK----QVFLDMKLLDIDNTVAKGVEN-- 79  Sinorhizobium melilot...
Q8P3D7  14 LIFALDVPGHDEAIAWVDRLGe--SvaFYKIGMELLASGEyFHVLDALAKrNK----RVFVDLKFFDIPATVAGTIRR-- 85  Xanthomonas campestri...
Q9WYG7   3 PVLSLDMEDPIRFIDENGSFE------VVKVGHNLAIHGK--KIFDELAKrNl----KIILDLKFCDIPSTVERSIKS-- 68  Thermotoga maritima MSB8
Q25566 261 LCVAADITSKDDLLKLADETGPeiC--MLKTHIDTLDDQPdEQFTQQLKElAKkhnfLIFEDRKLADIGQVVKQQYARgp 338 Naegleria gruberi
Q92AH6   4 PIIALDFQTYQEVEAFLAQFSG--EslSVKVGMELFYSNG-PAIVEKIKQqNH----AIFLDLKLHDIPNTVKSAMIG-- 74  Listeria innocua Clip...
4MUZ_A  24 LILALDVMDGEKAMEIAKKVAEhvD--RIKVNYPLVLSAG-VGIMKRLSEi-K----PVIADFKIADVPYTSSLIARI-- 93  Archaeoglobus fulgidus

3RU6_A  99 -VSKLGVDMINIHASAG-KIAIQEVMTRLSKFs---KrPLVLAVSALTSFDEenffS------IYRQKIEEAVINFSKIS 167 Campylobacter jejuni ...
Q8PV88  77 -VFKAGADAVIVQGFTG-RDSLDACIEVASKY----G-KDVFVVSEMSHPGG----A------EFLQSAAEAIAKMAVEA 139 Methanosarcina mazei Go1
O29333  74 -AFENSAESVIVHGFVG-SDTLREVCRVAEEF----G-GKVYAVTELSSPGG----E------EFMSAVSLKIVEKAKEA 136 Archaeoglobus fulgidu...
Q9PIC1  75 -VSKLGVDMINIHASAG-KIAIQEVMTRLSKFs---KrPLVLAVSALTSFDE----Enf--fsIYRQKIEEAVINFSKIS 143 Campylobacter jejuni ...
Q92SN8  80 -IVKMGVSMLTLHAY---PKAMKSAVEAARG-----SnLCLLGVTVLTSMDE----Qdvi-daGYEYDPHSLVLRRAEQA 145 Sinorhizobium melilot...
Q8P3D7  86 -LSQWPVSYCTVHGW---HAGMLEAAAAANQ-----GdMRLLAVTVLTSMGR----Pdla-amGIDREPVDVVVERALAA 151 Xanthomonas campestri...
Q9WYG7  69 -WDHPAIIGFTVHSCAG-YESVERALSATDK--------HVFVVVKLTSMEG------------SLEDYMDRIEKLNKLG 126 Thermotoga maritima MSB8
Q25566 339 fKIAQWSDLCNSHLVSGgSATVKALKESLKEEni-tEpRGLLLIAQMSTEGA-----------TTGESTKQEALKVALEN 406 Naegleria gruberi
Q92AH6  75 -LAKLGVDMVNVHASGG-KKMMEAAREGLEIGstsgKrPKLIAVTQLTSTSE----TdmqkeqLVKASLLESVLHYSDLT 148 Listeria innocua Clip...
4MUZ_A  94 -AFENSAESVIVHGFVG-SDTLREVCRVAEEF----G-GKVYAVTELSSPGG----E------EFMSAVSLKIVEKAKEA 156 Archaeoglobus fulgidus

3RU6_A 168 YENGLDGMVCSVFESKKIKEHTSsNFLTLTPGIRPfg-eTNDdqKRvanlAMARENLSDYIVVGRPIYKNENPRAVCEKI 246 Campylobacter jejuni ...
Q8PV88 140 GAFGLVAPATRPERVKEIRKIIGdRLTIISPGVGA----QGG--KA----SDVISAGADWVIVGRSIYKAESPKEAACEI 209 Methanosarcina mazei Go1
O29333 137 GCHGLIAPSTRIERLREIRKAAG-DMEILCPGIGA----QKG--S-----IEAVKYA-DGIIVGRGIYASGNPAEEARKL 203 Archaeoglobus fulgidu...
Q9PIC1 144 YENGLDGMVCSVFESKKIKEHTSsNFLTLTPGIRPfg-eTNDdqKRvanlAMARENLSDYIVVGRPIYKNENPRAVCEKI 222 Campylobacter jejuni ...
Q92SN8 146 RAAGMGGIVCSAEEAAAVRKIIGgDMALVTPGIRPag-aEKGdqKRvmtpADALRAGSSHLVVGRPIVAAPDPLAASRAI 224 Sinorhizobium melilot...
Q8P3D7 152 QAAGIDGVIASGQEAGMIRRATGpAFSIVCPGIRPgg-pVGDdqQRtvgvAQAFADGADAIVVGRPIRLANDPAAAAAAI 230 Xanthomonas campestri...
Q9WYG7 127 CDFVLPGPWAKALREKIKG-------KILVPGIRMev--kADdqKDvvtlEEMKGIA-NFAVLGREIYLSENPREKIKRI 196 Thermotoga maritima MSB8
Q25566 407 PDF-VSGFICQSKLRDDLDQ-----FLYCTPGVRLdvkgDSLgqQYnspeYVVCEKKCDVIIVGRGIYhDKERQNAAKLY 480 Naegleria gruberi
Q92AH6 149 KQAGLDGVVCSALEADEIKLQNGsDFLRVTPGIRLas-dATDdqIRvvtpEKARSIGSSNIVVGRSITRANDPVAAYNQV 227 Listeria innocua Clip...
4MUZ_A 157 GCHGLIAPSTRIERLREIRKAAG-DMEILCPGIGAq--------Kg---sIEAVKY-ADGIIVGRGIYASGNPAEEARKL 223 Archaeoglobus fulgidus

3RU6_A 247 L 247 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Q8PV88 210 A 210 Methanosarcina mazei Go1
O29333 204 R 204 Archaeoglobus fulgidus DSM 4304
Q9PIC1 223 L 223 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Q92SN8 225 L 225 Sinorhizobium meliloti 1021
Q8P3D7 231 Q 231 Xanthomonas campestris pv. campestris str. ATCC 33913
Q9WYG7 197 K 197 Thermotoga maritima MSB8
Q25566 481 R 481 Naegleria gruberi
Q92AH6 228 L 228 Listeria innocua Clip11262
4MUZ_A 224 R 224 Archaeoglobus fulgidus
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