Conserved Protein Domain Family
SPRYD7

?
cd12880: SPRYD7 
SPRY domain-containing protein 7
This family contains SPRY domain-containing protein 7 (also known as SPRY domain-containing protein 7 or CLL deletion region gene 6 protein homolog or CLLD6 or chronic lymphocytic leukemia deletion region gene 6 protein homolog). In humans, CLLD6 is highly expressed in heart, skeletal muscle, and testis as well as cancer cell lines. It also has cross-species conservation, suggesting that it is likely to carry out important cellular processes.
Statistics
?
PSSM-Id: 293938
Aligned: 31 rows
Threshold Bit Score: 217.837
Created: 1-May-2012
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
EEB12265      37 MGHEVVIVKNglRMCGSGGCLASAPLvQNKSYFEVKLQq-gGVWGCGVASRSADVNaapg-ghdsESWVLCsdlcirHNQ 114 human body louse
EFW43291      55 MAPDCVIVKAgkRLCGSGAVLATAPLaQDKSYFEVKLQa-aGRWGVGVASRKEDLAavpl--gneNSWVLRsdsttwHKQ 131 Capsaspora owcz...
CBY20989      37 MGLDAVIVKNgtRVCGTGAVLGTAAImQDKAYFEVKVQs-dGIWGCGVAAEQCDLNkvp---tvdKSWVLTsertiqKEG 112 Oikopleura dioica
Q19577        46 MGKNVVILKEgeRICGIGGAIATVPIvQNKAYFQVTVQq-tGTWGIGLGQKQSPFDkvp---cteKFWGIRdngdiaKEN 121 Caenorhabditis ...
ADY44337       1 MGDDVVLLKNgqRICGSGGALATAPIvQNKAYFQVSIQq-sGVWGIGVANRSINLNsvp---isaNSWVLRhtgevvANG 76  pig roundworm
GAA53683      46 AGPTVVLLKNclRICGHGCARSVVPIlQDKAYFEVKIQc-tGHWAVGLCSSKTPLAsvenlgidkASWVLRedscvwYSG 124 Clonorchis sine...
CCD60139      41 AAPSVLILKSglRICSNGAARTNIPIiQDYAYYEVKLQnygGSWGIGLCTVNTLLDsiqsltndsSCWILRndmkiwSRG 120 Schistosoma man...
EFV55470     157 SGENVVLLKDstRICGSGASLCTAPLlQDNSYFEIKIQq-aGSWGVGVASPDVDLNripl-gkdmKSCVLRcdgkvyRND 234 Trichinella spi...
XP_003389614  32 MGVDCVVVKSgrRVCGTGAALANAPIvQDKSYFEVKIQc-gGVWGVGLATPTVSLDtvpl-gtdtNSWVLTsegttvHNS 109 Amphimedon quee...
ESO02084      36 TGQGVVLVKNstRICGSGSALANTPIqQNKAYFEAKLQs-aGVWGLGLANRNCNLQsslq-gadqNSWVLRqdgkiyHKN 113 Helobdella robusta
EEB12265     115 Ssiykv-nnqiQEGDIIGIWYDHlELNFSIN--------GKPLECPVTg------IKGTVYPCLYVDDGAILDIIVD--- 176 human body louse
EFW43291     132 Qlgsv--dvkfEEGDVLGFSYDHvELNIFHN--------GKALNCPIIg------VRGTVYPAFYVDEGAILDVIFH--- 192 Capsaspora owcz...
CBY20989     113 Kdves--ieeiCEGDVIGVTYDHvELQFYLN--------SNPIGNPVTg------IRGKIYPILYVDESAILDAEFV--- 173 Oikopleura dioica
Q19577       122 Evvakm-tktvEEGDVVGVAYDHvELKFYVN--------GKAVEDVITg------VRGPVYPMVYVDDSAILDLKFK--- 183 Caenorhabditis ...
ADY44337      77 Evvdkl-lepiEEGDCIGVAFDHvDLKFYKN--------GVQLPVSISn------VRGQVFPLVYVDDSAILDATFR--- 138 pig roundworm
GAA53683     125 Vklarl-ktplEEGSVLGLTYDHvELRFYINga----atGLINEQSAQsmdgwtgMKGVLYPVVGVAENAVLDVGFNrk- 198 Clonorchis sine...
CCD60139     121 Hvigql-kqsvEEGDVIGVIYDKgKLRFTINgdtahvysEQTEQIPLFid----sTGEVLYPVLGVEDGTVLDVAFTans 195 Schistosoma man...
EFV55470     235 Qvvcek-qllvEEGDHVRIAYNHvDLQFAINd------sNDWISTPAM-------KGVVVFPVVYADDGAIIDVSFS--- 297 Trichinella spi...
XP_003389614 110 Qtisrg-kqkpNEGDIIGISYDHvEMNFFLN--------GKSMDLPVTg------IRGTVFPAIYVDDGAILDVQFM--- 171 Amphimedon quee...
ESO02084     114 EergklseqlpQEGDVLGFTYDHvDLKIFLN--------GKPTNLSFSg------IKGTVYPLVYVDDGAIIDMIFS--- 176 Helobdella robusta
EEB12265     177 -NFCYQPPSGFDKIMIEQSLL 196 human body louse
EFW43291     193 -TFVHTPPTGFTEIMLEKNIL 212 Capsaspora owczarzaki ATCC 30864
CBY20989     174 -HFRNMPPSGFGQIMFEQNIL 193 Oikopleura dioica
Q19577       184 -NFTEAPPAGFGEILVEQTIL 203 Caenorhabditis elegans
ADY44337     139 -LFSYNAPPGYEEIMLEQTLL 158 pig roundworm
GAA53683     199 hFYFPPPQSDFKEILFEKELL 219 Clonorchis sinensis
CCD60139     196 fNYLPLSVEGFGEIKFQKEVT 216 Schistosoma mansoni
EFV55470     298 -EFNCPPPDRYQPILLEQSLF 317 Trichinella spiralis
XP_003389614 172 -DFTYPPPDGYDQILLERNLL 191 Amphimedon queenslandica
ESO02084     177 -RFVHEPPDGYEEIMIEKSLL 196 Helobdella robusta
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap